ArticleEpidemiology and psychiatric sciences2025
Associations between social determinants of health and mental health disorders among U.S. population: a cross-sectional study.
Article in Epidemiology and psychiatric sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Evaluating Intra-household Agreement on Multi-domain Family-Level Social Determinants of Health and Exploring Individual Correlates of Agreement in Two Southern California Family Studies.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Comparison of Emergency Department Patients with Salpingitis and Oophoritis with and without Documented Social Determinants of Health.The western journal of emergency medicine · 2026Article
- Social determinants disadvantage score and liver health in the All of Us Research Program.European journal of epidemiology · 2026Article
- Associations between neighborhood disorder and mental health service utilization in theDiscover public health · 2026Article
- Social Determinants of Health as a Predictor of Psoriasis Risk: Preliminary Findings from a National Survey.Clinical, cosmetic and investigational dermatology · 2026Article
- Working-age patients with medically unexplained oral symptoms who receive public assistance in Japan.Scientific reports · 2025Article
- Cumulative Social Determinants of Health Are Associated With Anxiety: A Weighted Quantile Sum Analysis.Inquiry : a journal of medical care organization, provision and financingArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe impact of social determinants of health (SDOH) on mental health is increasingly realized. A comprehensive study examining the associations of SDOH with mental health disorders has yet to be accomplished. This study evaluated the associations between five domains of SDOH and the SDOH summary score and mental health disorders in the United States.
methodsWe analyzed data from a diverse group of participants enrolled in the All of Us research programme, a research programme to gather data from one million people living in the United States, in a cross-sectional design. The primary exposure was SDOH based on Healthy People 2030: education access and quality, economic stability, healthcare access and quality, social and community context, and neighbourhood and built environment. A summary SDOH score was calculated by adding each adverse SDOH risk (any SDOH vs. no SDOH). Our primary outcomes were diagnoses of major depression (MD) (i.e., major depressive disorder, recurrent MD or MD in remission) and anxiety disorders (AD) (i.e., generalized AD and other anxiety-related disorders). Multiple logistic regression models were used to determine adjusted odd ratios (aORs) for MD and/or ADs after controlling for covariates.
resultsA total of 63,162 participants with MD were identified (22,277 [35.3%] age 50-64 years old; 41,876 [66.3%] female). A total of 77,624 participants with AD were identified (25,268 [32.6%] age 50-64 years old; 52,224 [67.3%] female). Factors associated with greater odds of MD and AD included having less than a college degree, annual household income less than 200% of federal poverty level, housing concerns, lack of transportation, food insecurity, and unsafe neighbourhoods. Having no health insurance was associated with lower odds of both MD and AD (aOR, 0.48; 95% confidence interval [CI], 0.46-0.51 and aOR, 0.44; 95% CI, 0.42-0.47, respectively). SDOH summary score was strongly associated with the likelihood of having MD and AD (aOR, 1.97; 95% CI, 1.89-2.06 and aOR, 1.69; 95% CI, 1.63-1.75, respectively).
conclusionsThis study found associations between all five domains of SDOH and the higher odds of having MD and/or AD. The strong correlations between the SDOH summary score and mental health disorders indicate a possible use of the summary score as a measure of risk of developing mental health disorders.
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