Evidence map›Paper›PMID 39810406›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2025

Ankle-Brachial Index as a Predictor of Acute Ischemic Cerebrovascular Event After Central Retinal Artery Occlusion.

Dong-Bo Liu, Bing-Xian Zhang, Yao Zhou, Jian-Hua Zhao, Jie-Wen Zhang

Abstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong-Bo LiuDepartment of Neurology, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou, Henan, China.
Bing-Xian ZhangDepartment of Neurology, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou, Henan, China.
Yao ZhouDepartment of Neurology, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou, Henan, China.
Jian-Hua ZhaoDepartment of Neurology, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou, Henan, China.
Jie-Wen ZhangDepartment of Neurology, Henan Provincial People's Hospital (People's Hospital of Zhengzhou University), Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Identifying patients at higher risk of acute ischemic cerebrovascular events (AICE) following central retinal artery occlusion (CRAO) is crucial for secondary prevention of stroke. This study aimed to investigate whether a low ankle-brachial index value is associated with an increased risk of AICE after CRAO. MATERIAL AND METHODS We prospectively analyzed patients who were admitted to our hospital because of CRAO between February 2019 and March 2023 and whose ankle-brachial index was no greater than 1.40. We explored the potential association between the index and risk of AICE (defined as ischemic stroke or transient ischemic attack) within 1 year after occlusion. Patients were classified into 2 groups according to whether their index was low (≤0.90) or normal (0.91-1.40). RESULTS Of the 335 patients in the final analysis, 110 (32.8%) had an ankle-brachial index of ≤0.90 and 89 (26.6%) experienced AICE during 1-year follow-up. In univariable analysis, patients with a low index had a significantly higher AICE incidence than those with a normal index (36.4% vs 21.8%, P<0.01). Multivariable logistic regression analysis, adjusting for variables associated with low index, identified low index as an independent predictor of AICE after CRAO (OR 1.864, 95% CI 1.095-3.174, P=0.022). CONCLUSIONS Low values of the ankle-brachial index may independently predict higher risk of AICE after CRAO. This index may serve as a non-invasive screening tool for patients with CRAO who require intensified secondary stroke prevention.

Indexed as

Ankle Brachial IndexBrain IschemiaIschemic StrokeRetinal Artery OcclusionAgedFemaleHumansIschemic Attack, TransientMaleMiddle AgedProspective StudiesRisk FactorsStroke

Identifiers

PMID39810406
PMCPMC11744880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.