Evidence map›Paper›PMID 39810147›Full record

ArticleBMC public health2025

The effects of deprivation, age, and regional differences in COVID-19 mortality from 2020 to 2022: a retrospective analysis of public provincial data.

Anqi A Chen, Elizabeth M Renouf, Charmaine B Dean, X Joan Hu

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anqi A ChenDepartment of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada. angela_chen_6@sfu.ca.
Elizabeth M RenoufDepartment of Civil Engineering, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Charmaine B DeanDepartment of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
X Joan HuDepartment of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada.

Funding

NSERC EIDM RGPID-560514-2020
6 · The paper itself

Abstract

backgroundCoronavirus disease (COVID-19) quickly spread around the world after its initial identification in Wuhan, China in 2019 and became a global public health crisis. COVID-19 related hospitalizations and deaths as important disease outcomes have been investigated by many studies while less attention has been given to the relationship between these two outcomes at a public health unit level. In this study, we aim to establish the relationship of counts of deaths and hospitalizations caused by COVID-19 over time across 34 public health units in Ontario, Canada, taking demographic, geographic, socio-economic, and vaccination variables into account.

methodsWe analyzed daily data of the 34 health units in Ontario between March 1, 2020 and June 30, 2022. Associations between numbers of COVID-19 related deaths and hospitalizations were explored over three subperiods according to the availability of vaccines and the dominance of the Omicron variant in Ontario. A generalized additive model (GAM) was fit in each subperiod. Heterogeneity across public health units was formulated via a random intercept in each of the models.

resultsMean daily COVID-19 deaths increased quickly as daily hospitalizations increased, particularly when daily hospitalizations were less than 20. In all the subperiods, mean daily deaths of a public health unit was significantly associated with its population size and the proportion of confirmed cases in subjects over 60 years old. The proportion of fully vaccinated (2 doses of primary series) people in the 60 + age group was a significant factor after the availability of the COVID-19 vaccines. The deprivation index, a measure of poverty, had a significantly positive effect on COVID-19 mortality after the dominance of the Omicron variant in Ontario. Quantification of these effects was provided, including effects related to public health units.

conclusionsThe differences in COVID-19 mortality across health units decreased over time, after adjustment for other covariates. In the last subperiod when most public health protections were released and the Omicron variant dominated, the least advantaged group might suffer higher COVID-19 mortality. Interventions such as paid sick days and cleaner indoor air should be made available to counter lifting of health protections.

Indexed as

COVID-19HospitalizationSocial DeprivationAdultAgedAge FactorsCOVID-19 VaccinesFemaleHumansMaleMiddle AgedOntarioRetrospective StudiesSARS-CoV-2Socioeconomic FactorsYoung AdultCOVID-19 VaccinesCOVID-19 hospitalizationsCOVID-19 vaccinesGeneralized additive modelsPublic reporting of health care dataRandom effectsSARS-CoV-2 infection

Identifiers

PMID39810147
PMCPMC11730143

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.