Evidence map›Paper›PMID 39809946›Full record

SynthesisNeurosurgical review2025

Neuroendoscopic surgery versus craniotomy for basal ganglia hemorrhage: a systematic review and meta-analysis of randomized controlled trials.

Kaike Lobo, Cláudia Santos, Pedro Campos, Larah Oliveira, Vithor Ely Bortolin da Silva

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaike LoboDepartment of Neurosurgery, State University of Pará, Belém, Brazil. kaikelobo.med@gmail.com.ORCID https://orcid.org/0009-0000-4844-2877
Cláudia SantosDepartment of Neurosurgery, UniFG Centro Universitário, Guanambi, Brazil.ORCID https://orcid.org/0009-0001-4720-5711
Pedro CamposDepartment of Neurosurgery, Universidade Federal de Mato Grosso, Cuiabá, Brazil.ORCID https://orcid.org/0000-0001-9303-1102
Larah OliveiraDepartment of Neurosurgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0009-0004-0543-4729
Vithor Ely Bortolin da SilvaDepartment of Neurosurgery, Hospital Heliópolis, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1740-850X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal ganglia hemorrhage (BGH) is a prevalent site for intracerebral hemorrhage. Although neuroendoscopy (NE) surgery has emerged as a less invasive alternative to craniotomy (CT), the optimal surgical method remains debatable. This systematic review and meta-analysis aimed to compare the efficacy and safety of NE versus CT in the management of BGH. A systematic search of PubMed, Embase, Cochrane Library, and Web of Science databases was conducted to identify eligible randomized controlled trials (RCTs) comparing NE surgery with CT in BGH patients. Outcomes included mortality, hematoma evacuation rate, good functional outcome (GFO), operative time, infection, pulmonary infection, and postoperative complication. Risk of bias was assessed with Cochrane's ROB-2 tool. Four RCTs were included, comprising 423 patients. NE surgery showed no significant benefit in mortality (p = 0.12) and GFO (p = 0.18). However, NE was associated with a higher hematoma evacuation rate (p = 0.007), shorter operative time (p < 0.00001), and lower rates of infection (p < 0.0001), pulmonary infection (p < 0.0001), and postoperative complications (p < 0.00001). Future research should be designed to assess whether hematoma evacuation using either technique improves outcomes in comparison to optimal medical management in this population.

Indexed as

Basal Ganglia HemorrhageCraniotomyNeuroendoscopyHumansPostoperative ComplicationsRandomized Controlled Trials as TopicTreatment OutcomeBasal ganglia hemorrhageCraniotomyIntracerebral hemorrhageMeta-analysisNeuroendoscopy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.