Evidence map›Paper›PMID 39809861›Full record

ReviewNature reviews. Chemistry2025

Catechol redox maintenance in mussel adhesion.

Stephanie X Wang, J Herbert Waite

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Catechol Derivative-Based Bioadhesives: Molecular Design for Precision Medical Adhesion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephanie X WangDepartment of Chemistry & Biochemistry, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID 0009-0000-9108-6177
J Herbert WaiteDepartment of Chemistry & Biochemistry, University of California Santa Barbara, Santa Barbara, CA, USA. hwaite@ucsb.edu.ORCID 0000-0003-4683-7386

Funding

National Science Foundation DMR 1720256
6 · The paper itself

Abstract

Catechol-functionalized proteins in mussel holdfasts are essential for underwater adhesion and cohesion and have inspired countless synthetic polymeric materials and devices. However, as catechols are prone to oxidation, long-term performance and stability of these inventions awaits effective antioxidation strategies. In mussels, catechol-mediated interactions are stabilized by 'built-in' homeostatic redox reservoirs that restore catechols oxidized to quinones. Mussel byssus has a typical 'core-shell' architecture in which the core is a degradable fibrous block copolymer consisting of collagen and fibroin coated by robust protein networks stabilized by bis-catecholato-metal and tris-catecholato-metal ion complexes. The coating is well-adapted to protect the core against abrasion, hydrolysis and microbial attack, but it is not impervious to oxidative damage, which, during function, is promptly repaired by redox poise via coacervated catechol-rich and thiol-rich reducing interlayers and inclusions. However, when the e

Indexed as

BivalviaCatecholsAnimalsOxidation-ReductioncatecholCatechols

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.