ArticleNature communications2025
Modeling bacterial interactions uncovers the importance of outliers in the coastal lignin-degrading consortium.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Visible Light-Driven Copper-Catalyzed Asymmetric Synthesis via Sequential C(spAngewandte Chemie (International ed. in English) · 2026Article
- Unveiling the Acidic Backbone of Baijiu: A Comprehensive Review on Composition, Metabolic Pathways, and Quality Implications.Comprehensive reviews in food science and food safety · 2026Review
- Metabolic Modelling Facilitates the Design of Synthetic Communities by Simplifying Natural Microbial Communities.Environmental microbiology · 2026Article
- Microbial Decomposition of Lignin to Methane Reduces Net Blue Carbon Benefit Across China's Saltmarshes.Global change biology · 2026Article
- Reimagining Lignin Valorization: Synthetic Biology-Enabled Sustainable Aromatic Carbon Biomanufacturing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- SubCom analysis: dissecting microbial community functions into taxon-specific contributions and interaction contexts.Microbiome · 2026Article
- Plant Biomass Depolymerization by Oxidoreductases: Structural Characteristics, Synergy Mechanism, and Evolutionary Adaptation.Journal of agricultural and food chemistry · 2026Review
- Functional roles of degraders and non-degraders in anaerobic trophic networks converting lignocellulose into monocarboxylates.NPJ biofilms and microbiomes · 2026Article
- Plastic Degradation Potential and Metagenomic Analysis of an Enriched Gut Microbial Consortium fromMicroorganisms · 2026Article
- Defining metabolic niches for marine microbial heterotrophs.Science advances · 2026Article
- Review
- Multiscale metabolic engineering in biological lignin valorization.Innovation (Cambridge (Mass.)) · 2025Review
- Mutualism between degraders and nondegraders stabilizes the function of a natural biopolymer-degrading community.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Nitrogen-shaped microbiotas with nutrient competition accelerate early-stage residue decomposition in agricultural soils.Nature communications · 2025Article
- Modeling bacterial interactions uncovers the importance of outliers in the coastal lignin-degrading consortium.Nature communications · 2025Article
- Decoding emergent properties of microbial community functions through subcommunity observations and interpretable machine learning.The ISME journal · 2025Article
- Temperature mediates biodiversity and metabolism of culturable lignocellulose-degrading consortia from intertidal wetlands.The ISME journal · 2025Article
- Roles of microbial interactions in determining the establishment and function of synthetic consortium inoculants for soil applications.The ISME journal · 2025Article
- Oral microbiome is related to lepidopteran herbivore performance by lignin degradation.ISME communications · 2025Article
- Ecological design of high-performance synthetic microbial communities: from theoretical foundations to functional optimization.ISME communications · 2025Review
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Authors and funding
7 authors.
Funding
Abstract
Lignin, as the abundant carbon polymer, is essential for carbon cycle and biorefinery. Microorganisms interact to form communities for lignin biodegradation, yet it is a challenge to understand such complex interactions. Here, we develop a coastal lignin-degrading bacterial consortium (LD), through "top-down" enrichment. Sequencing and physiological analyses reveal that LD is dominated by the lignin degrader Pluralibacter gergoviae (>98%), with additional rare non-degraders. Interestingly, LD, cultured in lignin-MB medium, significantly enhances cell growth and lignin degradation as compared to P. gergoviae alone, implying a role of additional outliers. Using genome-scale metabolic models, metabolic profiling and culture experiments, modeling of inter-species interactions between P. gergoviae, Vibrio alginolyticus, Aeromonas hydrophila and Shewanella putrefaciens, unravels cross-feeding of amino acids, organic acids and alcohols between the degrader and non-degraders. Furthermore, the sub-population ratio is essential to enforce the synergy. Our study highlights the unrecognized role of outliers in lignin degradation.
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