Evidence map›Paper›PMID 39809722›Full record

ArticleHematological oncology2025

Acalabrutinib in High-Risk Chronic Lymphocytic Leukaemia Naïve Patients: An Italian Multicenter Retrospective Observational Real-Life Experience.

Idanna Innocenti, Annamaria Tomasso, Diana Giannarelli, Lydia Scarfò, Roberta Murru, Andrea Visentin, Anna Maria Frustaci, Francesca Morelli, Candida Vitale, Antonio Mosca and 22 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Hematological oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Idanna InnocentiDepartment of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.
Annamaria TomassoHematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.ORCID https://orcid.org/0009-0005-5361-7463
Diana GiannarelliFacility of Epidemiology and Biostatistics, GSTeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Lydia ScarfòStrategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.
Roberta MurruHematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS G. Brotzu, Cagliari, Italy.
Andrea VisentinHematology Unit, Department of Medicine-DIMED, University of Padua, Padova, Italy.ORCID https://orcid.org/0000-0003-0271-7200
Anna Maria FrustaciDepartment of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.ORCID https://orcid.org/0000-0003-2587-7901
Francesca MorelliDepartment of Experimental and Clinical Medicine, University of Florence, Firenze, Italy.
Candida VitaleDepartment of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy.
Antonio MoscaHematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.
Alessandro SannaHematology, Department of Oncology, AOU Careggi, Firenze, Italy.
Giuliana FarinaHematology and Medical Oncology, AORN Sant'Anna e San Sebastiano, Caserta, Italy.
Roberta LaureanaHematology, Department of Biomedicine and Prevention Tor Vergata, University of Rome, Roma, Italy.
Massimo GentileHematology Unit AO of Cosenza, Cosenza, Italy.ORCID https://orcid.org/0000-0002-8504-3231
Andrea GalitziaDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Raffaella PasqualeSOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy.
Francesco AutoreDepartment of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.ORCID https://orcid.org/0000-0002-7868-7469
Jacopo OlivieriSOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy.
Azzurra RomeoHematology and Stem Cell Transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, Latina, Italy.
Marina DeodatoDepartment of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
Luca StirparoHematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.
Andrea CorbingiHematology and Stem Cell Transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, Latina, Italy.
Vanessa InnaoUOC di Ematologia, Azienda Ospedaliera di rilievo nazionale di alta specializzazione, ARNAS-Garibaldi di Catania, Catania, Italy.
Francesca PerutelliDepartment of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy.
Francesca MartiniStrategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.
Paolo SportolettiDepartment of Medicine and Surgery, Institute of Hematology, Centro di Ricerca Emato Oncologica (CREO), University of Perugia, Perugia, Italy.
Alberto FresaHematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.ORCID https://orcid.org/0000-0002-8084-9009
Maria Ilaria Del PrincipeHematology, Department of Biomedicine and Prevention Tor Vergata, University of Rome, Roma, Italy.
Alessandra TedeschiDepartment of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.ORCID https://orcid.org/0000-0001-8724-2771
Marta CosciaDepartment of Medicine and Surgery, University of Insubria, and Hematology Division, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.
Paolo GhiaStrategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.
Luca LaurentiDepartment of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.ORCID https://orcid.org/0000-0002-8327-1396

Funding

AstraZeneca
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acalabrutinibcBTKiCLLhigh risk

Identifiers

PMID39809722
PMCPMC11732783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.