Evidence map›Paper›PMID 39809560›Full record

ArticleBMJ open2025

Risk, incidence and predictors of venous thromboembolism among patients attending the emergency department of tertiary care hospitals in Addis Ababa city, Ethiopia: a multicentre prospective study.

Worku Degefa, Minyahil Alebachew Woldu, Desalew Mekonnen, Alemseged Beyene Berha

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Worku DegefaDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Minyahil Alebachew WolduDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Desalew MekonnenDepartment of Internal Medicine, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Alemseged Beyene BerhaDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia alembeyene98@gmail.com.ORCID http://orcid.org/0000-0003-3825-2863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to assess the risk, incidence and predictors of venous thromboembolism (VTE) among patients admitted to the emergency department of tertiary hospitals in Addis Ababa city, Ethiopia.

designA multicentre hospital-based prospective follow-up study was conducted.

settingThe study was conducted in three tertiary care hospitals in Addis Ababa city, Ethiopia: Tikur Anbesa Specialized Hospital, Addis Ababa Burn Emergency and Trauma Hospital and St. Paulos Hospital Millennium Medical College.

participantsA total of 422 patients admitted to the adult emergency wards of the selected hospitals during the study period were included.

main outcome measuresThe study assessed the level of VTE risk, incidence and independent risk factors for VTE.

resultsNearly half (51.7%) of the study participants were male, with a mean age of 49.36 (±17.12) years. Around one-third of patients (130, 30.8%) were unable to perform physical activity, and about two-thirds had comorbid illnesses. The most common admission diagnosis was trauma (23.7%), followed by infectious disease (19.2%). More than two-thirds (70.64%) of patients were at high risk of developing VTE according to the Padua Risk Prediction Score. Eighteen patients (4.3%) were diagnosed with VTE during their emergency stay. Multivariate Cox regression analysis revealed that patients who were physically active prior to admission (adjusted hazard ratio (AHR)=0.67, 95% CI 0.082 to 1.579, p=0.014) and those receiving pharmacological prophylaxis (AHR=0.167, 95% CI 0.037 to 0.768, p=0.021) were found to have a protective effect against the risk of developing VTE. Conversely, patients with acute infection (AHR=8.169, 95% CI 1.045 to 63.854, p=0.045) and active cancer (AHR=5.133, 95% CI 1.241 to 21.093, p=0.023) had a higher risk of VTE incidence.

conclusionThe study found that the risk and incidence of VTE were high among patients in the emergency department. Absence of pharmacological prophylaxis, physical inactivity prior to admission, active cancer and acute infection were identified as independent predictors of VTE incidence during emergency ward stays.

Indexed as

Emergency Service, HospitalVenous ThromboembolismAdultAgedEthiopiaFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedProspective StudiesRisk FactorsTertiary Care CentersACCIDENT & EMERGENCY MEDICINEAuditEmergency DepartmentsEmergency Service, HospitalPaediatric intensive & critical careVascular medicine

Identifiers

PMID39809560
PMCPMC11751836

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