ArticleClinical and experimental otorhinolaryngology2025
Effectiveness of Septal Swell Body Reduction for Patients With Nasal Airway Obstruction: A Systematic Review and Meta-Analysis.
Article in Clinical and experimental otorhinolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- The Efficacy of Intranasal Insulin in the Treatment of Post-Viral Persistent Olfactory Dysfunction: A Systematic Review.Clinical and experimental otorhinolaryngology · 2026Review
- Flagging Septum: New Concept to Describe Septal Support Loss and Its Impact on the Nasal Cycle.Plastic and reconstructive surgery. Global open · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectivesThe septal swell body, a distinct anatomical structure in the anterior nasal septum, is a significant contributor to nasal obstruction and affects airflow dynamics and nasal resistance. This meta-analysis evaluated the impact of septal swell body volume reduction (SSBVR).
methodsA systematic review was conducted using PubMed, Scopus, Embase, Web of Science, and Cochrane databases through October 2024. Outcomes included changes in nasal obstruction scores, cross-sectional area, and nasal airway resistance before and after SSBVR. Standardized mean differences (SMDs) were calculated, and the effectiveness of SSBVR combined with turbinate surgery was compared to turbinate surgery alone.
resultsSeven studies involving 232 patients were analyzed. SSBVR significantly improved cross-sectional area (SMD, -1.05; 95% CI, -1.88 to -0.21) and nasal airway resistance (SMD, -0.67; 95% CI, -0.89 to -0.45). Nasal obstruction scores showed significant improvements up to 12 months (SMD, 2.54; 95% CI, 1.81 to 3.26). When SSBVR was added to turbinate surgery, nasal obstruction scores improved further (SMD, 0.47; 95% CI, 0.24 to 0.70) compared to turbinate surgery alone, though no significant differences were found in cross-sectional area or nasal airway resistance. Subgroup analyses demonstrated time-dependent improvements in nasal obstruction scores and varied effectiveness based on treatment modality.
conclusionSSBVR significantly improves nasal obstruction and airflow metrics, with additional benefits when combined with turbinate surgery. Further randomized trials are warranted to validate these findings and guide optimal treatment strategies.
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