Evidence map›Paper›PMID 39809367›Full record

Trial reportIndian heart journal

Efficacy of Angiotensin Receptor Neprilysin Inhibitor (ARNI) in right ventricular systolic dysfunction and preserved LV ejection fraction: A randomized clinical trial.

Rohit Mathur, Anil Baroopal, Chaina Ram Chaudhary, Afjal Hakim, Manoj Verma

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rohit MathurDepartment of Cardiology, Dr. S. N. Medical College, Jodhpur, India. Electronic address: drrohitmathur@rediffmail.com.
Anil BaroopalDepartment of Cardiology, Dr. S. N. Medical College, Jodhpur, India.
Chaina Ram ChaudharyDepartment of Tuberculosis and Chest Diseases, Dr. S. N. Medical College, Jodhpur, India.
Afjal HakimDepartment of Community Medicine, Dr. S. N. Medical College, Jodhpur, India.
Manoj VermaDepartment of Community Medicine, Dr. S. N. Medical College, Jodhpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensin Receptor Neprilysin Inhibitor (ARNI) has not shown to be promising in Heart failure with preserved LVEF. Role of ARNI in Right ventricular systolic dysfunction with preserved LVEF needs to be evaluated. We took 50 patients with isolated RV systolic dysfunction and divided them into two groups of 25 patients each- Conventional treatment and ARNI in addition to conventional treatment. We found that the ARNI group showed a significant improvement in NYHA class, all the echo parameters of RV size, RV function and NT-pro BNP levels at 4 weeks and 12 weeks.

Indexed as

AminobutyratesAngiotensin Receptor AntagonistsHeart VentriclesNeprilysinStroke VolumeTetrazolesVentricular Dysfunction, RightVentricular Function, RightBiphenyl CompoundsDrug CombinationsEchocardiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedAminobutyratesAngiotensin Receptor AntagonistsBiphenyl CompoundsDrug CombinationsNeprilysinsacubitril and valsartan sodium hydrate drug combinationTetrazolesValsartanAngiotensin Receptor Neprilysin InhibitorHeart failureNT-pro BNPRight ventricular systolic dysfunction

Identifiers

PMID39809367
PMCPMC11977159

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.