Evidence map›Paper›PMID 39809342›Full record

Trial reportContemporary clinical trials2025

Multilevel intervention for follow-up of abnormal FIT in the safety-net: IMProving Adherence to Colonoscopy through Teams and Technology (IMPACTT).

Katarina Wang, Jeanette Wong, Leslie Avilez, Kristan Olazo, Samuel Olanrewaju, Charles E McCulloch, Rena Pasick, Shreya Patel, Ma Somsouk, Urmimala Sarkar

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06191185 (IMProving Adherence to Colonoscopy Through Teams and Technology), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06191185 naenrolling by invitationnot on this map

IMProving Adherence to Colonoscopy Through Teams and Technology

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2027Enrolled2,000ConditionsColon Cancer, Cancer Colorectal, Colorectal CancerArmsBPB, No PIN, BPB, PIN, No BPB, PIN, No BPB, No PIN
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katarina WangSchool of Medicine and Dentistry, University of Rochester, Rochester, New York, USA; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Jeanette WongDivision of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA; Action Research Center for Health Equity, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, USA.
Leslie AvilezDivision of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA; Action Research Center for Health Equity, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, USA.
Kristan OlazoDivision of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA; Action Research Center for Health Equity, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, USA.
Samuel OlanrewajuSchool of Medicine, University of California San Francisco, San Francisco, California, USA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Rena PasickSchool of Medicine, University of California San Francisco, San Francisco, California, USA.
Shreya PatelDivision of Gastroenterology, University of California San Francisco, San Francisco, California, USA.
Ma SomsoukAction Research Center for Health Equity, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, USA; School of Medicine, University of California San Francisco, San Francisco, California, USA; Division of Gastroenterology, University of California San Francisco, San Francisco, California, USA.
Urmimala SarkarDivision of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA; Action Research Center for Health Equity, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, California, USA; School of Medicine, University of California San Francisco, San Francisco, California, USA. Electronic address: Urmimala.Sarkar@ucsf.edu.

Funding

IMProving Adherence to Colonoscopy through Teams and Technology (IMPACTT)R01CA271031 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Urmimala Sarkar, Ma Somsouk · 2022 to 2026
$3.3M
NCI NIH HHS R01 CA271031
6 · The paper itself

Abstract

backgroundFecal immunochemical testing (FIT) is a widely used first step for colorectal cancer (CRC) screening. Abnormal FIT results require a colonoscopy for screening completion and CRC diagnosis, but the rate of timely colonoscopy is low, especially among patients in safety-net settings. Multi-level factors at the clinic- and patient-levels influence colonoscopy completion after an abnormal FIT. Our study aims to implement a multi-level approach consisting of a clinic- and patient-level intervention to improve the completion of diagnostic colonoscopy after an abnormal FIT.

methodsWe will test a multilevel intervention with one safety-net system across 12 primary care clinics - a clinic-level intervention using a stepped wedge design and a patient-level intervention with patient-level randomization. At the clinic level, we will implement a "best practices bundle" to improve workflow for primary care providers and staff using a stepped-wedge design. At the patient level, we will randomize 2000 patients to receive text messages and call reminders or usual care.

resultsFor the main analysis, we will use a mixed effects logistic model to assess the impact of the clinic intervention on the primary outcome (completion of colonoscopy within 180 days after abnormal FIT). Secondary outcomes include median days to colonoscopy completion, rate of referral to colonoscopy at 42 days, rate of scheduled colonoscopy at 56 days, and bowel preparation quality at colonoscopy. DISCUSSION: This study will assess the extent to which a multi-level intervention can improve timely colonoscopy completion in a diverse patient population cared for in a safety-net setting.

trial registrationNCT, NCT06191185. Registered 20 December 2023, https://clinicaltrials.gov/study/NCT06191185.

Indexed as

ColonoscopyColorectal NeoplasmsEarly Detection of CancerPatient ComplianceSafety-net ProvidersFemaleHumansOccult BloodPrimary Health CareRandomized Controlled Trials as TopicReminder SystemsText MessagingWorkflowCancer health disparitiesColorectal cancer screeningDigital healthSafety-net health systems

Identifiers

PMID39809342
PMCPMC12693720

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.