Evidence map›Paper›PMID 39809317›Full record

ArticleVox sanguinis2025

Notification of blood donors who test positive for transfusion-transmissible infections.

Sheila F O'Brien, Kiyuri Naicker, Lori Osmond, Kelly Holloway, Steven J Drews, Mark Bigham, Mindy Goldman

Abstract read
In one paragraph

Article in Vox sanguinis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sheila F O'BrienEpidemiology & Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-5332-2789
Kiyuri NaickerEpidemiology & Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.
Lori OsmondEpidemiology & Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.
Kelly HollowayDonation and Policy Studies, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0003-3867-1072
Steven J DrewsMicrobiology, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0003-2519-1109
Mark BighamMedical Laboratory and Stem Cell Services, Canadian Blood Services, Ottawa, Ontario, Canada.
Mindy GoldmanDonation and Policy Studies, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0001-9904-9952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesDespite screening procedures, a few blood donors confirm positive for transfusion-transmissible infections and are deferred. Effective notification of laboratory results is essential to ensure that donors are advised of confirmed results and to seek medical care. Here we report results from post-notification interviews of Canadian Blood Services donors. MATERIALS AND

methodsOver 17 years, 2006-2022, all donors with confirmed positive results for hepatitis B virus (HBV), hepatitis C virus (HCV), human T-cell lymphotropic virus (HTLV) and syphilis were notified by registered mail of their result and advised to see a physician. In a separate communication, all donors were later invited to participate in a scripted interview asking whether they tested positive for an infection; if yes, which one, what their reaction was, whether they consulted a physician and whether public health contacted them. Frequencies of responses were calculated.

resultsOf 2654 donors with confirmed positive test results, 876 (33%) participated; 90% said they were informed of a positive test result. Of these, about a quarter did not know for which infection they were positive. Most were surprised, and some were sad or disappointed. Most saw a physician after notification (77%). About two-thirds with HBV or HCV said they were contacted by public health, slightly fewer (58%) with syphilis, 27% of those with HTLV.

conclusionMost donors recalled being notified and were aware of their positive test, but details of the infection were sometimes not understood or recalled, and not all donors consulted a physician about the infection.

Indexed as

Blood-Borne InfectionsBlood DonorsTransfusion ReactionAdultCanadaDisease NotificationFemaleHepatitis BHepatitis CHumansMaleMiddle AgedSyphilisblood donorsinfectious disease testingnotification

Identifiers

PMID39809317
PMCPMC12017946

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.