Evidence map›Paper›PMID 39809273›Full record

ArticleStructure (London, England : 1993)2025

Mg

Benjamin Russell Lewis, Muhammad R Uddin, Katie M Kuo, Laila M N Shah, Nicola J Harris, Paula J Booth, Dietmar Hammerschmid, James C Gumbart, Helen I Zgurskaya, Eamonn Reading

Abstract read
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

  • Update of
    Mg2024
5 · Who and what money

Authors and funding

10 authors.

Benjamin Russell LewisDepartment of Chemistry, Britannia House, 7 Trinity Street, King's College London, London, SE1 1DB, UK.
Muhammad R UddinDepartment of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019, USA.
Katie M KuoSchool of Physics, Georgia Institute of Technology, 837 State Street NW, Atlanta, GA 30332, USA.
Laila M N ShahDepartment of Chemistry, Britannia House, 7 Trinity Street, King's College London, London, SE1 1DB, UK.
Nicola J HarrisDepartment of Chemistry, Britannia House, 7 Trinity Street, King's College London, London, SE1 1DB, UK.
Paula J BoothDepartment of Chemistry, Britannia House, 7 Trinity Street, King's College London, London, SE1 1DB, UK.
Dietmar HammerschmidDepartment of Chemistry, Britannia House, 7 Trinity Street, King's College London, London, SE1 1DB, UK; School of Biological Sciences, University of Southampton, Southampton, SO17 1BJ, UK.
James C GumbartSchool of Physics, Georgia Institute of Technology, 837 State Street NW, Atlanta, GA 30332, USA; School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive NW, Atlanta, GA 30332, USA. Electronic address: gumbart@physics.gatech.edu.
Helen I ZgurskayaDepartment of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019, USA. Electronic address: elenaz@ou.edu.
Eamonn ReadingDepartment of Chemistry, Britannia House, 7 Trinity Street, King's College London, London, SE1 1DB, UK; School of Biological Sciences, University of Southampton, Southampton, SO17 1BJ, UK. Electronic address: e.reading@soton.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tripartite resistance nodulation and cell division multidrug efflux pumps span the periplasm and are major drivers of multidrug resistance among gram-negative bacteria. Cations, such as Mg

Indexed as

ATP-Binding Cassette, Sub-Family C ProteinsEscherichia coliEscherichia coli ProteinsMagnesiumMembrane Transport ProteinsBacterial Outer Membrane ProteinsCarrier ProteinsCrystallography, X-RayDrug Resistance, Multiple, BacterialHistidineHydrogen-Ion ConcentrationLipoproteinsModels, MolecularProtein BindingAcrAB-TolC protein, E coliAcrA protein, E coliATP-Binding Cassette, Sub-Family C ProteinsBacterial Outer Membrane ProteinsCarrier ProteinsEscherichia coli ProteinsHistidineLipoproteinsMagnesiumMembrane Transport Proteinsantimicrobial resistancebacterial efflux assayshydrogen/deuterium exchange mass spectrometrymolecular dynamics simulationsmultidrug efflux pumps

Identifiers

PMID39809273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.