Evidence map›Paper›PMID 39808968›Full record

ArticleNeurophysiologie clinique = Clinical neurophysiology2025

Refining computer-assisted SEEG planning with spatial priors - A novel comparison of implantation strategies across adult and paediatric centres.

Debayan Dasgupta, Aswin Chari, Mehdi Khan, Friederike Moeller, Zubair Tahir, Andrew W McEvoy, Anna Miserocchi, John S Duncan, Rachel E Sparks, Martin Tisdall

Abstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurophysiologie clinique = Clinical neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Debayan DasguptaVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. Electronic address: debayan.dasgupta@ucl.ac.uk.
Aswin ChariVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK; Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.
Mehdi KhanUniversity College London Medical School, London, WC1E 6BT, UK; Department of Neurosurgery, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK.
Friederike MoellerDepartment of Neurophysiology, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK.
Zubair TahirDepartment of Neurosurgery, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK.
Andrew W McEvoyVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.
Anna MiserocchiVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.
John S DuncanDepartment of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Rachel E SparksSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, WC2R 2LS, UK.
Martin TisdallDevelopmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK; Department of Neurosurgery, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesComputer-assisted planning (CAP) allows faster SEEG planning and improves grey matter sampling, orthogonal drilling angles to the skull, reduces risk scores and minimises intracerebral electrode length. Incorporating prior SEEG trajectories enhances CAP planning, refining output with centre-specific practices. This study significantly expands on the previous work, compares priors libraries between two centres, and describes differences between SEEG in adults and children in these centres.

methods98 adults and 61 children who underwent SEEG implantation as part of epilepsy surgery investigations were included. Priors libraries were created for each population, clustered by target regions and subdivided by cortical approaches. The libraries were coregistered and quantitatively and qualitatively compared.

resultsThe average number of implanted electrodes per patient was higher in paediatric patients than adults (13.6 vs 8.0). Paediatric implantations focused more on the insula than adult implantations (38.0 % vs 13.5 %), with similar proportions of electrodes implanted in the temporal and parietal lobes, and a higher proportion of adult electrodes in the frontal and orbitofrontal regions (40.6 % vs 24.0 %). Correspondence between the priors libraries was high. We present an example of a complex insular implantation planned with paediatric spatial priors and illustrate resultant SEEG recordings. DISCUSSION: The use of centre-specific spatial priors allows the incorporation of surgeon-specific and unit-specific preferences into automated planning. We compare implantation styles between a paediatric and an adult centre, discussing similarities and differences. This tool allows centres to compare practice and represents an effective way to analyse implantation strategies that is agnostic to method of implantation.

Indexed as

ElectrocorticographyElectroencephalographyEpilepsySurgery, Computer-AssistedAdolescentAdultCerebral CortexChildChild, PreschoolElectrodes, ImplantedFemaleHumansMaleMiddle AgedYoung AdultComputer-assisted planningEpilepsy surgeryIntracranial EEGSpatial priorsStereoelectroencephalography (SEEG)Surgical planning

Identifiers

PMID39808968
PMCPMC7619480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.