Evidence map›Paper›PMID 39808889›Full record

ArticleEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology2025

PET-CT-based host metabolic (PETMet) features are associated with pathologic response in gastroesophageal adenocarcinoma.

Charlie White, Vetri Sudar Jayaprakasam, Megan Tenet, Laura H Tang, Mark A Schattner, Yelena Y Janjigian, Steven B Maron, Heiko Schöder, Steven M Larson, Mithat Gönen and 5 more

Abstract read
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In one paragraph

Article in European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prognostic significance of liver-to-muscle FDG uptake ratio and ınflammatory biomarkers in small cell lung cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Charlie WhiteDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Vetri Sudar JayaprakasamDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Megan TenetDivision of Surgical Oncology, Department of Surgery, Northwell Health, New Hyde Park, NY, USA.
Laura H TangDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mark A SchattnerGastroenterology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Yelena Y JanjigianGastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Steven B MaronGastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Heiko SchöderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Steven M LarsonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mithat GönenDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jashodeep DattaDivision of Surgical Oncology, Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.
Daniel G CoitGastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Audrey MauguenDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Vivian E StrongGastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gerardo A VitielloDivision of Surgical Oncology, Department of Surgery, Northwell Health, New Hyde Park, NY, USA; Gastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: gvitiello@northwell.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundMATERIALS AND

methodsA prospectively maintained institutional database of gastroesophageal cancer patients was queried for pretreatment PET-CTs, demographics, and clinicopathologic variables.

resultsTwo-hundred and one patients with distal gastroesophageal (48 %) or gastric (52 %) adenocarcinoma were included. PET-CT-derived scores were independently associated with PR after adjusting for clinical variables. CART and Random Forest methods identified critical split points of non-tumor tissue

conclusionsPretreatment host PETMet features may be useful for predicting PR after neoadjuvant therapy in gastroesophageal cancer. Unsupervised decision trees indicate that low

Indexed as

AdenocarcinomaEsophageal NeoplasmsPositron Emission Tomography Computed TomographyStomach NeoplasmsAdipose TissueAgedDecision TreesEsophagogastric JunctionFemaleFluorodeoxyglucose F18HumansLiverMaleMiddle AgedMuscle, SkeletalRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalsGastric cancerPathologic responsePatient metabolic profilingPET-CTPETMet

Identifiers

PMID39808889
PMCPMC12068993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.