Evidence map›Paper›PMID 39808784›Full record

ArticleJMIR formative research2025

Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study.

Ruben Vonderlin, Tali Boritz, Carola Claus, Büsra Senyüz, Saskia Mahalingam, Rachel Tennenhouse, Stefanie Lis, Christian Schmahl, Jürgen Margraf, Tobias Teismann and 3 more

Abstract read
In one paragraph

Article in JMIR formative research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ruben VonderlinDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0000-0003-4570-5648
Tali BoritzDepartment of Psychology, York University, Toronto, ON, Canada.ORCID 0000-0002-6066-5624
Carola ClausMental Health Research and Treatment Center, Ruhr-University Bochum, Bochum, Germany.ORCID 0009-0001-6079-6632
Büsra SenyüzDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0000-0002-9674-3655
Saskia MahalingamDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0009-0008-3221-9193
Rachel TennenhouseCentre for Addiction and Mental Health, Borderline Personality Disorder Clinic, Toronto, ON, Canada.ORCID 0009-0001-5851-3912
Stefanie LisGerman Center for Mental Health (DZPG), Partner Site Mannheim - Heidelberg - Ulm, Mannheim, Germany.ORCID 0000-0002-8051-2756
Christian SchmahlDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0000-0003-0141-0821
Jürgen MargrafMental Health Research and Treatment Center, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0001-5207-7016
Tobias TeismannMental Health Research and Treatment Center, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0002-6498-7356
Nikolaus KleindienstDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0000-0002-1696-2488
Shelley McMainCentre for Addiction and Mental Health, Borderline Personality Disorder Clinic, Toronto, ON, Canada.ORCID 0000-0002-0269-5876
Martin BohusDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0000-0002-1768-3608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential of telehealth psychotherapy (ie, the online delivery of treatment via a video web-based platform) is gaining increased attention. However, there is skepticism about its acceptance, safety, and efficacy for patients with high emotional and behavioral dysregulation.

objectiveThis study aims to provide initial effect size estimates of symptom change from pre- to post treatment, and the acceptance and safety of telehealth dialectical behavior therapy (DBT) for individuals diagnosed with borderline personality disorder (BPD).

methodsA total of 39 individuals meeting the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders [Fifth Edition]) criteria for BPD received 1 year of outpatient telehealth DBT at 3 sites in Germany and Canada. Effect size estimates were assessed using pre-post measures of BPD symptoms, dissociation, and quality of life. Safety was evaluated by analyzing suicide attempts and self-harm. Additionally, acceptance and feasibility, satisfaction with treatment, useability of the telehealth format, and the quality of the therapeutic alliance were assessed from both therapists' and patients' perspectives. All analyses were conducted on both the intention-to-treat (ITT) and according-to-protocol (ATP) samples.

resultsAnalyses showed significant and large pre-post effect sizes for BPD symptoms (d=1.13 in the ITT sample and d=1.44 in the ATP sample; P<.001) and for quality of life (d=0.65 in the ITT sample and d=1.24 in the ATP sample). Dissociative symptoms showed small to nonsignificant reductions. Self-harm behaviors decreased significantly from 80% to 28% of all patients showing at least 1 self-harm behavior in the last 10 weeks (risk ratio 0.35). A high dropout rate of 38% was observed. One low-lethality suicide attempt was reported. Acceptance, feasibility, and satisfaction measures were high, although therapists reported only moderate useability of the telehealth format.

conclusionsTelehealth DBT for BPD showed large pre-post effect sizes for BPD symptoms and quality of life. While the telehealth format appeared feasible and well-accepted, the dropout rate was relatively high. Future research should compare the efficacy of telehealth DBT with in-person formats in randomized controlled trials. Overall, telehealth DBT might offer a potentially effective alternative treatment option, enhancing treatment accessibility. However, strategies for decreasing drop-out should be considered.

trial registrationGerman Clinical Trials Register DRKS00027824; https://drks.de/search/en/trial/DRKS00027824.

Indexed as

Borderline Personality DisorderDialectical Behavior TherapyPatient Acceptance of Health CareAdultCanadaFemaleGermanyHumansMaleMiddle AgedPatient SatisfactionPilot ProjectsQuality of LifeTelemedicineTreatment OutcomeYoung Adultacceptanceborderline personality disorderdialectical behavior therapyinternetmentalonlineonline psychotherapypersonality disorderspsychiatricpsychiatrypsychotherapytelehealthtelemedicinevirtual psychotherapy

Identifiers

PMID39808784
PMCPMC11775487

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.