Evidence map›Paper›PMID 39808425›Full record

GuidelineJAMA2025

Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement.

US Preventive Services Task Force, Wanda K Nicholson, Michael Silverstein, John B Wong, David Chelmow, Tumaini Rucker Coker, Esa M Davis, Carlos Roberto Jaén, Marie Krousel-Wood, Sei Lee and 9 more

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in JAMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. A randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy of the synbiotic medical food, SBD111, for the clinical dietary management of bone loss in menopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Trial
  4. Trial
  5. Article
  6. Article
  7. In vivo mechanical assessment of cortical bone rigidity enhances fracture discrimination beyond DXA in postmenopausal women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  8. Review
  9. Explainable Plasma Proteomics-Based Machine Learning for Osteoporosis Diagnosis, Prognosis, and Protein Biomarker Discovery in the UK Biobank.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  10. Management of glucocorticoid-induced osteoporosis in rheumatic diseases.Best practice & research. Clinical rheumatology · 2026
    Review
  11. Article
  12. AI-derived opportunistic screening using chest radiographs identifies age- and sex-associated bone mineral density patterns and supports earlier osteoporosis evaluation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. The Neurology of Menopause.Current neurology and neuroscience reports · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

US Preventive Services Task Force
Wanda K NicholsonGeorge Washington University, Washington, DC.
Michael SilversteinBrown University, Providence, Rhode Island.
John B WongTufts University School of Medicine, Boston, Massachusetts.
David ChelmowVirginia Commonwealth University, Richmond.
Tumaini Rucker CokerUniversity of Washington, Seattle.
Esa M DavisUniversity of Maryland School of Medicine, Baltimore.
Carlos Roberto JaénUniversity of Texas Health Science Center, San Antonio.
Marie Krousel-WoodTulane University, New Orleans, Louisiana.
Sei LeeUniversity of California, San Francisco.
Li LiUniversity of Virginia, Charlottesville.
Carol M MangioneUniversity of California, Los Angeles.
Gbenga OgedegbeNew York University, New York, New York.
Goutham RaoCase Western Reserve University, Cleveland, Ohio.
John M RuizUniversity of Arizona, Tucson.
James StevermerUniversity of Missouri, Columbia.
Joel TsevatUniversity of Texas Health Science Center, San Antonio.
Sandra Millon UnderwoodUniversity of Wisconsin, Milwaukee.
Sarah WieheIndiana University, Bloomington.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Osteoporotic fractures are associated with psychological distress, subsequent fractures, loss of independence, reduced ability to perform activities of daily living, and death. Objective: The US Preventive Services Task Force (USPSTF) commissioned a systematic review to evaluate the evidence on the benefits and harms of screening for osteoporosis to prevent fractures in adults 40 years or older with no known diagnosis of osteoporosis or history of fragility fracture. Population: Adults 40 years or older without known osteoporosis or history of fragility fractures. Evidence Assessment: The USPSTF concludes with moderate certainty that screening for osteoporosis to prevent osteoporotic fractures in women 65 years or older has moderate net benefit. The USPSTF concludes with moderate certainty that screening for osteoporosis to prevent osteoporotic fractures in postmenopausal women younger than 65 years at increased risk has moderate net benefit. The USPSTF concludes that the evidence is insufficient and the balance of benefits and harms for screening for osteoporosis to prevent osteoporotic fractures in men cannot be determined. Recommendation: The USPSTF recommends screening for osteoporosis to prevent osteoporotic fractures in women 65 years or older. (B recommendation) The USPSTF recommends screening for osteoporosis to prevent osteoporotic fractures in postmenopausal women younger than 65 years who are at increased risk for an osteoporotic fracture as estimated by clinical risk assessment. (B recommendation) The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for osteoporosis to prevent osteoporotic fractures in men. (I statement).

Indexed as

Advisory CommitteesMass ScreeningOsteoporosisOsteoporotic FracturesPreventive Health ServicesAbsorptiometry, PhotonAdultAgedAge FactorsBone DensityFemaleHumansMaleMiddle AgedPostmenopauseRisk Assessment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.