Evidence map›Paper›PMID 39808399›Full record

ReviewProbiotics and antimicrobial proteins2025

Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health.

Alice Njolke Mafe, Great Iruoghene Edo, Patrick Othuke Akpoghelie, Tayser Sumer Gaaz, Emad Yousif, Khalid Zainulabdeen, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Rapheal Ajiri Opiti, Yasal Garba and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Effect of AG1Frontiers in nutrition · 2026
    Trial
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Frontiers in microbiology · 2026
    Article
  11. Review
  12. Review
  13. Lactic acid fermentation ofFood chemistry: X · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alice Njolke MafeDepartment of Biological Sciences, Faculty of Science, Taraba State University Jalingo, Jalingo, Taraba State, Nigeria.
Great Iruoghene EdoDepartment of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria. greatiruo@gmail.com.
Patrick Othuke AkpoghelieDepartment of Food Science and Technology, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria.
Tayser Sumer GaazDepartment of Prosthetics and Orthotics Engineering, College of Engineering and Technologies, Al-Mustaqbal University, Babylon, Iraq.
Emad YousifDepartment of Chemistry, College of Sciences, Al-Nahrain University, Baghdad, Iraq.
Khalid ZainulabdeenDepartment of Chemistry, College of Sciences, Al-Nahrain University, Baghdad, Iraq.
Endurance Fegor IsojeDepartment of Science Laboratory Technology (Biochemistry Option), Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria.
Ufuoma Augustina IgbukuDepartment of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria.
Rapheal Ajiri OpitiDepartment of Petroleum Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria.
Yasal GarbaDepartment of Information Engineering, College of Information Engineering, Al-Nahrain University, Baghdad, Iraq.
Arthur Efeoghene Athan EssaghahDepartment of Urban and Regional Planning, Faculty of Environmental Sciences, Delta State University of Science and Technology, Ozoro, Nigeria.
Dina S AhmedDepartment of Chemical Industries, Institute of Technology-Baghdad, Middle Technical University, Baghdad, Iraq.
Huzaifa UmarOperational Research Centre in Healthcare, Near East University, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review paper delves into the role of probiotics and food bioactives in influencing gut health and overall well-being, within the context of probiotics and food bioactives, emphasizing their roles in modulating inflammation, gut microbiota, and metabolic health. Probiotics are defined as live microorganisms that confer health benefits to the host, primarily through their impact on the gut microbiome; a complex community of microorganisms crucial for maintaining health. The review aims to elucidate how probiotics, incorporated into both traditional and modern food systems, can enhance gut health and address metabolic disorders. It examines the types of probiotics present in various foods and their mechanisms of action, including their effects on immune function and metabolic health. By exploring the links between probiotics and health outcomes such as digestive health, immune support, and mental health, the review identifies specific conditions where probiotics show significant promise. Hurldes such as inconsistencies in research findings, variability in probiotic strains, and dosages are addressed. The paper also suggests future research directions, including the potential for personalized probiotic interventions. The review concludes by summarizing key findings and emphasizing the critical role of probiotics in food systems for promoting overall health and mitigating metabolic diseases.

Indexed as

Gastrointestinal MicrobiomeInflammationMetabolic DiseasesProbioticsAnimalsHumansFood BioactivesGut MicrobiomeInflammationMetabolic HealthProbiotics

Identifiers

PMID39808399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.