Evidence map›Paper›PMID 39808386›Full record

ReviewAnimal models and experimental medicine2025

Exploring the neuroprotective benefits of phytochemicals extracted from indigenous edible fruits in Bangladesh.

Sumon Roy, Sajib Chandra Roy, Mehrukh Zehravi, Sherouk Hussein Sweilam, Rajib Das, Mylsamy Palanisamy, Venkata Lakshamana Sagar Dantinapalli, Selvaraja Elumalai, Jeetendra Kumar Gupta, Mohammed Ali Alshehri and 4 more

Abstract readReview
In one paragraph

Review in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sumon RoyDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh.
Sajib Chandra RoyDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh.
Mehrukh ZehraviDepartment of Clinical Pharmacy, College of Dentistry & Pharmacy, Buraydah Private Colleges, Buraydah, Saudi Arabia.
Sherouk Hussein SweilamDepartment of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Rajib DasDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh.
Mylsamy PalanisamyBoehringer Ingelheim Pharmaceuticals Inc., Powell, Ohio, USA.
Venkata Lakshamana Sagar DantinapalliVeranova, Davens, Massachusetts, USA.
Selvaraja ElumalaiGranules Pharmaceuticals Inc., Chantilly, Virginia, USA.
Jeetendra Kumar GuptaInstitute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India.
Mohammed Ali AlshehriDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia.
Mohammed AsiriDepartment of Clinical Laboratory Sciences, College of Applied Medical Science, King Khalid University, Abha, Saudi Arabia.
Irfan AhmadDepartment of Clinical Laboratory Sciences, College of Applied Medical Science, King Khalid University, Abha, Saudi Arabia.
Mohamed H NafadyDepartment of Radiology and Medical Imaging Technology, Faculty of Applied Health Science Technology, Misr University for Science and Technology, Giza, Egypt.
Talha Bin EmranDepartment of Pharmacy, Faculty of Health and Life Sciences, Daffodil International University, Dhaka 1207, Bangladesh.ORCID 0000-0003-3188-2272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing incidence of neurodegenerative diseases (NDs) and the constraints of existing treatment methods have spurred a keen interest in investigating alternative therapies. Medicinal plants, renowned for their long-standing use in traditional medicine, offer a hopeful avenue for discovering new neuroprotective agents. This study emphasizes the potential neuroprotective characteristics of edible fruit plants in Bangladesh, specifically focusing on their traditional folk medicine uses for neurological disorders. This study provides an in-depth overview of the different types of edible fruit trees in Bangladesh and their phytochemicals, including flavonoids, terpenoids, and phenolic acids. This work examines the scientific data supporting the neuroprotective properties of bioactive chemicals from plants. It further explores the mechanisms by which these compounds work to counteract oxidative stress, decrease inflammation, and stimulate neurogenesis. Moreover, the study investigates toxicological characteristics and bioactive components of some fruits, emphasizing the importance of further investigation to measure their safety profile comprehensively. This thorough study highlights the potential benefits of Bangladesh's edible fruit trees as a rich source of neuroprotective chemicals. It also shows that additional research might lead to novel approaches for improving brain functioning and preventing NDs.

Indexed as

FruitNeurodegenerative DiseasesNeuroprotective AgentsPhytochemicalsPlant ExtractsAnimalsBangladeshHumansMedicine, TraditionalNeuroprotective AgentsPhytochemicalsPlant ExtractsBangladeshedible fruit plantsneuroprotectionphytochemicalstraditional medicine

Identifiers

PMID39808386
PMCPMC11871099

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.