Evidence map›Paper›PMID 39808261›Full record

ReviewForensic science, medicine, and pathology2025

MALDI-MSI: A potential game changer in forensic sciences.

Asma Jamshaid, Saadia Noreen, Tanveer Khalid

Abstract readReview
PubMed Publisher
In one paragraph

Review in Forensic science, medicine, and pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Asma JamshaidCenter for Research in Molecular Medicine, Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.
Saadia NoreenCenter for Research in Molecular Medicine, Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan. sadi.noreen@gmail.com.
Tanveer KhalidSchool of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix-assisted laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) is an analytical technique used for the spatial mapping of drugs, explosives, and organic samples, making it a game-changer in Forensic examination. It detects a wide range of biomolecules in their native state without specific tags, antibodies, labels, and dyes. This review aims to highlight the advancement of MALDI-MSI over time and its impact on Forensic Science due to high-resolution molecular imaging. To foster the development of forensic investigations the utility of MALDI-MSI in six different broad areas, Latent Fingerprinting division, forensic toxicology division, Crime Scene Reconstruction and investigation division, Sex crimes, forensic trichology division, question document analysis, is explored in this review. MALDI-MSI possesses a unique strength of molecular imaging of biomolecules without complex preparation from diverse sample types. In the future, the sensitivity and detection limits of MALDI-MSI can be enhanced and its instrumental size should be reduced to perform on-site investigation.

Indexed as

Forensic SciencesMolecular ImagingSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationForensic ToxicologyHumansFinger printing and MALDI MSIForensic proteomics and MALDI MSIHair examination and MALDI MSIMALDI MSI in forensicsToxicological analysis with MALDI MSIVariants of MALDI

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.