Evidence map›Paper›PMID 39808082›Full record

ArticleEnvironmental health perspectives2025

Hair Straightener Use in Relation to Prevalent and Incident Fibroids in the Sister Study with a Focus on Black Women.

Kemi Ogunsina, Katie M O'Brien, Alexandra J White, Che-Jung Chang, Symielle A Gaston, Chandra L Jackson, Dale P Sandler

Abstract read
In one paragraph

Article in Environmental health perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kemi OgunsinaEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.ORCID 0000-0002-1616-0944
Katie M O'BrienEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Alexandra J WhiteEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Che-Jung ChangEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Symielle A GastonEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Chandra L JacksonEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.ORCID 0000-0002-6776-0018

Funding

Social and Environmental Determinants of Health EquityZIAES103325 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JACKSON, CHANDRA · 2017 to 2025
$12.7M
Intramural NIH HHS ZIA ES103325
6 · The paper itself

Abstract

backgroundUterine fibroids disproportionately affect Black women, and exposure to chemicals from hair relaxers or straighteners ("straighteners") may contribute to fibroid development.

objectivesWe examined the association between straightener use and prevalent young-onset uterine fibroids (diagnosed before age 36 y), as well as incident fibroids (diagnosed age 36-60 y), with a focus on Black women. We also examined differences in associations across birth cohorts as proxies for formulation changes.

methodsData from 4,162 Black women in the Sister Study, a prospective cohort of women 35-74 y of age (enrolled 2003-2009), were analyzed. We used logistic regression to estimate odds ratios (ORs) for the association of straightener use at 10-13 y of age and self-reported young-onset fibroids. We used Cox regression to assess hazard ratios (HRs) for straightener use (age 10-13 y and in 12 months before enrollment) and incident fibroids among 779 premenopausal Black women. Similar analyses were conducted in 40,782 non-Hispanic White women.

resultsOver 70% of Black women used straighteners. In comparison with no use, any [ DISCUSSION: Hair straightener use may be positively associated with fibroid risk. https://doi.org/10.1289/EHP14493.

Indexed as

Hair PreparationsLeiomyomaUterine NeoplasmsAdolescentAdultAgedBlack or African AmericanChildFemaleHumansIncidenceMiddle AgedPrevalenceProspective StudiesHair Preparations

Identifiers

PMID39808082
PMCPMC11730732

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.