Evidence map›Paper›PMID 39807796›Full record

ArticleACS applied materials & interfaces2025

Silver Nanoparticles-Functionalized Textile against SARS-CoV-2: Antiviral Activity of the Capping Oleylamine Molecule.

Tamyres Bernardo de Souza, Alice S Rosa, Pamella Constantino-Teles, Vivian Neuza S Ferreira, Braulio S Archanjo, Carlos A G Soares, Paulo H S Picciani, Rafael A Allão Cassaro, Milene Dias Miranda, Giordano Poneti

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tamyres Bernardo de SouzaInstituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, Brazil.
Alice S RosaLaboratory of Morphology and Virus Morphogenesis, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, Rio de Janeiro 21041-250, Brazil.
Pamella Constantino-TelesLaboratory of Morphology and Virus Morphogenesis, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, Rio de Janeiro 21041-250, Brazil.
Vivian Neuza S FerreiraLaboratory of Morphology and Virus Morphogenesis, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, Rio de Janeiro 21041-250, Brazil.
Braulio S ArchanjoMaterials Metrology Division, National Institute of Metrology, Quality, and Technology, Duque de Caxias, Rio de Janeiro 25250-020, Brazil.ORCID 0000-0001-8145-7712
Carlos A G SoaresDepartamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-617, Brazil.
Paulo H S PiccianiInstituto de Macromoléculas Professora Eloisa Mano, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-598, Brazil.ORCID 0000-0001-8344-1482
Rafael A Allão CassaroInstituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, Brazil.ORCID 0000-0002-0789-2561
Milene Dias MirandaLaboratory of Morphology and Virus Morphogenesis, Oswaldo Cruz Institute, Fiocruz, Avenida Brasil, Rio de Janeiro 21041-250, Brazil.ORCID 0000-0003-0037-059X
Giordano PonetiInstituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-909, Brazil.ORCID 0000-0002-1712-4611

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 disease, triggered by SARS-CoV-2 virus infection, has led to more than 7.0 million deaths worldwide, with a significant fraction of recovered infected people reporting postviral symptoms. Smart surfaces functionalized with nanoparticles are a powerful tool to inactivate the virus and prevent the further spreading of the disease. Literature reports usually focus on the role of nanomaterial composition and size dispersion in evaluating their efficacy against SARS-CoV-2. Here, the anti-SARS-CoV-2 activity of oleylamine (OAm) used as a capping agent of silver nanoparticles is quantified for the first time. Spherical hydrophobic nanoparticles with 8 ± 2 nm diameter were prepared and characterized by Fourier transform infrared, dynamic light scattering, and transmission electron microscopy techniques. Biological assays showed that microgram amounts of nanoparticles, deposited on nonwoven textile obtained from surgical masks, efficiently inactivated up to 99.6(2)% of the virus with just 2 min of exposure. The virucidal activity of the corresponding amount of free OAm has been determined as well, reaching up to 67(1)% of activity for an exposure time of 10 min. Inductively coupled plasma optical emission spectrometry results pointed out a low leaching out of the nanoparticles in contact with water or culture medium. All in all, these results propose the capping molecules as an important chemical variable to be taken into account in the design of fast, efficient, and long-lasting anti-SARS-CoV-2 coatings.

Indexed as

AminesAntiviral AgentsMetal NanoparticlesSARS-CoV-2SilverTextilesAnimalsChlorocebus aethiopsCOVID-19COVID-19 Drug TreatmentHumansParticle SizeVero CellsAminesAntiviral AgentsoleylamineSilverantiviral activitycapping moleculedecontaminant agentoleylamineSARS-CoV-2silver nanoparticle

Identifiers

PMID39807796
PMCPMC11788990

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.