Evidence map›Paper›PMID 39807583›Full record

ArticleEnvironmental science & technology2025

Environmental Exposures Associated with Enteropathogen Infection in Six-Month-Old Children Enrolled in the ECoMiD Cohort along a Rural-Urban Gradient in Northern Ecuador†.

Kelsey J Jesser, Nicolette A Zhou, Caitlin Hemlock, Molly K Miller-Petrie, Jesse D Contreras, April Ballard, Andrea Sosa-Moreno, Manuel Calvopiña, Benjamin F Arnold, William Cevallos and 4 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Environmental Exposures and the Human Gut Resistome in Northwest Ecuador.medRxiv : the preprint server for health sciences · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kelsey J JesserDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-4074-3170
Nicolette A ZhouDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Caitlin HemlockDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Molly K Miller-PetrieDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Jesse D ContrerasDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, United States.
April BallardGangarosa Department of Environmental Health, Emory University, Atlanta, Georgia 30329, United States.
Andrea Sosa-MorenoDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, United States.
Manuel CalvopiñaOne Health Research Group, Facultad de Medicina, Universidad De Las Américas (UDLA), Quito 17901, Ecuador.
Benjamin F ArnoldF.I. Proctor Foundation and Department of Ophthalmology, University of California at San Francisco, San Francisco, California 94158, United States.
William CevallosCentro de Biomedicina, Universidad Central del Ecuador, Quito 170136, Ecuador.
Gabriel TruebaInstituto de Microbiología Colegio de Ciencias Biológicas y Ambientales, Universidad San Francisco de Quito, Quito 170901, Ecuador.
Gwenyth O LeeRutgers Global Health Institute, Rutgers University, New Brunswick, New Jersey 08901, United States.ORCID 0000-0002-7889-3852
Joseph N S EisenbergDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, United States.
Karen LevyDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-0968-9401

Funding

Environmetal Pathology/Toxicology Training ProgramT32ES007032 · NIEHS · UNIVERSITY OF WASHINGTON · PI FAUSTMAN, ELAINE M, ROSENFELD, MICHAEL E · 1985 to 2023
$10.7M
Graduate and Postdoctoral Training in ToxicologyT32ES012870 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2004 to 2026
$9.1M
Gut microbiome, enteric infections and child growth across a rurual urban gradientR01AI137679 · NIAID · UNIVERSITY OF WASHINGTON · PI EISENBERG, JOSEPH N. S., LEVY, KAREN · 2018 to 2023
$5.3M
Enteric Pathogen Force of Infection among Children using SerologyR01AI162867 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ARNOLD, BENJAMIN F · 2021 to 2025
$3.7M
Dynamic modeling of antagonism between enteric infection and undernutritionin infancyK01AI145080 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, GWENYTH O'NEILL · 2020 to 2024
$570k
NIAID NIH HHS K01 AI145080NIAID NIH HHS R01 AI137679NIAID NIH HHS R01 AI162867NIEHS NIH HHS T32 ES007032NIEHS NIH HHS T32 ES012870
6 · The paper itself

Abstract

Enteropathogens are major contributors to mortality and morbidity, particularly in settings with limited access to water, sanitation, and hygiene infrastructure. To assess transmission pathways associated with enteropathogen infection, we measured household environmental conditions and assayed 22 enteropathogens using TaqMan Array Cards in stool samples from 276 six-month-old children living in communities along a rural-urban gradient in Northern Ecuador. We utilized multivariable models, risk factor importance, and distance-based statistical methods to test factors associated with infection. Most children (89%) carried at least one pathogen, and 72% carried two or more. Bacterial infections (82% of participants) were more common than viruses (58%) or parasites (9.1%). Infants living in the urban site had decreased infection risks compared to those in rural locations. Improved water and sanitation were most predictive of reduced infection risk. Improved water was associated with decreased enterotoxigenic

Indexed as

Environmental ExposureAnimalsCohort StudiesEcuadorFecesFemaleHumansInfantMaleRural PopulationSanitationUrban Populationanimal exposureenteric infectionsenteropathogenshousehold environmental exposurewater, sanitation, and hygiene

Identifiers

PMID39807583
PMCPMC11740902

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.