Evidence map›Paper›PMID 39807504›Full record

ArticleHeliyon2025

Comparative immunohistochemical evaluation between primary and metastatic lesion in a feline osteosarcoma - A case report.

Lyvia Cabral Ribeiro Carvalho, Camila Barbosa Amaral, Bárbara Paula Dos Santos Batista, Ana Maria Reis Ferreira, Juliana da Silva Leite

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lyvia Cabral Ribeiro CarvalhoPrograma de Pós-Graduação em Medicina Veterinária - Clínica e Reprodução Animal, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Camila Barbosa AmaralDepartamento de Patologia e Clínica Veterinária, Faculdade de Veterinária, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Bárbara Paula Dos Santos BatistaPrograma de Pós-Graduação em Medicina Veterinária - Clínica e Reprodução Animal, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Ana Maria Reis FerreiraPrograma de Pós-Graduação em Medicina Veterinária - Clínica e Reprodução Animal, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Juliana da Silva LeitePrograma de Pós-Graduação em Medicina Veterinária - Clínica e Reprodução Animal, Universidade Federal Fluminense, Niterói, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline primary bone tumors are rare. Still, osteosarcoma (OSA) composes almost 80 % of malignant bone tumors in cats, affecting mostly elder feline individuals. Many differences are observed between canine and feline OSA regarding radiographic image and tumoral behavior, especially metastasis development. This case reports a cat diagnosed with digital osteosarcoma who developed pulmonary metastasis and other digital lesions over one year and half later. Simultaneous immunohistochemical analysis from both primary and metastatic tumoral tissues was performed using diagnostic and prognostic biomarkers panel for bone tumors in order to better understand such aggressive behavior in a feline patient. Similarities and differences from both lesions results revealed intrinsic mechanisms promoting osteosarcoma invasion in this cat.

Indexed as

Feline osteosarcomaHER-2Matrix metalloproteinasesPulmonary metastasisVimentin

Identifiers

PMID39807504
PMCPMC11728927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.