Evidence map›Paper›PMID 39807501›Full record

ArticleHeliyon2025

Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment.

Beibei Ge, Changqing Miao, Di Xu, Mingxia Li, Fang Xu, Xiaoxian Wang, Fen Chen, Yan Li, Yan Chen, Chanjuan Gong and 3 more

Abstract read
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Beibei GeDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China.
Changqing MiaoDepartment of Cardiology, Jiangyin People's Hospital, Jiangyin, 214499, People's Republic of China.
Di XuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Mingxia LiDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China.
Fang XuDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China.
Xiaoxian WangDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China.
Fen ChenDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China.
Yan LiDepartment of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Yan ChenDepartment of Cardiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210018, People's Republic of China.
Chanjuan GongDepartment of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Peng LiDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Fang WangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China.
Jing YaoDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to establish standard transesophageal echocardiographic (TEE) measurements of left ventricular (LV) morphology, function, and myocardial work parameters in healthy Beagle dogs using pressure-strain loops (PSL). Additionally, it sought to standardize optimal TEE imaging techniques and explore the potiential application of myocardial work analyis in veterinary medicine. Methods: Thirty-seven healthy male Beagle dogs were anesthetized, intubated, and mechanically ventilated for TEE examinations. LV systolic and diastolic function were evaluated, with simultaneous invasive femoral artery pressure measurements. Left ventricular global longitudinal strain (GLS), myocardial work parameters, PSL-derived metrics were analyzed. Results: The mean LV GLS was -16.0 ± 4.0 %, and the LV global myocardial work index (GWI) was 888 ± 298.6 mmHg∗%. Global Myocardial work efficiency (GWE) was 88 ± 3 %, while global myocardial wasted work (GWW) was 152 mmHg∗% (38-431 mmHg∗%). LV ejection fraction (LVEF) averaged 58.7 ± 4.4 %. Left ventricular end-diastolic (LVEDV) and end-systolic volume (LVESV) were 19.3 ± 5.2 ml and 8.0 ± 2.3 ml, respectively. Regional myocardial work analysis revealed significant differences between the interventricular septum and lateral wall. The lateral wall demonstrated reduced segmental work efficiency (SWE), work index (SWI), and constructive work (SCW) but higher wasted work (SWW) compared to the septum (p < 0.05). Conclusions: TEE provides detail morphological and functional assessments of the Beagle hearts, offering reference data for future studies. Myocardial work analysis presents a novel method for evaluate myocardial contractility and mechanical properties, with promising applicatons in veterinary medicine.

Indexed as

Beagle dogMyocardial workSpeckle tracking echocardiographyTransesophageal echocardiography

Identifiers

PMID39807501
PMCPMC11728980

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.