Evidence map›Paper›PMID 39807462›Full record

ArticleCureus2024

More Than a Haematoma: A Case of Aplastic Anemia.

Gaspar Fernandes, Tiago Ruivo, Óscar Ramos

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gaspar FernandesFamily Medicine, Family Health Unit (USF) Almedina, Local Health Unit of Trás-os-Montes and Alto Douro (ULSTMAD), Lamego, PRT.
Tiago RuivoFamily Medicine, Family Health Unit (USF) Almedina, Local Health Unit of Trás-os-Montes and Alto Douro (ULSTMAD), Lamego, PRT.
Óscar RamosFamily Medicine, Family Health Unit (USF) Almedina, Local Health Unit of Trás-os-Montes and Alto Douro (ULSTMAD), Lamego, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Easy bruising and ecchymosis are common symptoms in clinical practice, yet distinguishing benign from clinically significant cases can be challenging. We report the case of a 46-year-old woman who presented in December 2023 with easy bruising and increased menstrual flow, revealing new-onset pancytopenia in laboratory tests. Initially diagnosed with Acute Myeloid Leukemia inversion (inv) (16), subsequent results were inconclusive, leading to a diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH). Following clinical and analytical deterioration, a repeat bone marrow study in March 2024 identified Aplastic Anemia (AA). When evaluating easy bruising and ecchymosis, a thorough history and physical examination are essential, sometimes requiring further investigation and referral. AA is a rare and heterogeneous disease that requires excluding other causes of bone marrow failure for proper diagnosis. Its severity and the patient's age determine treatment and prognosis. This case underscores the importance of investigating common symptoms that may signal serious underlying conditions, as well as the complexities involved in diagnosing AA.

Indexed as

acquired aplastic anemiabone marrow failurebruisingecchymosislaboratory findings of pancytopeniasevere aplastic anemia

Identifiers

PMID39807462
PMCPMC11726393

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.