Evidence map›Paper›PMID 39807372›Full record

ArticleThe Lancet regional health. Western Pacific2025

Small mammals and associated infections in China: a systematic review and spatial modelling analysis.

Jin-Jin Chen, Chen-Long Lv, Tao Wang, Yan-He Wang, Tian-Le Che, Qiang Xu, Xue-Geng Hong, Ai-Ying Teng, Shen Tian, Yuan-Yuan Zhang and 6 more

Abstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jin-Jin ChenState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Chen-Long LvState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Tao WangThe 949th Hospital of Chinese PLA, Altay, Xinjiang, 836300, PR China.
Yan-He WangThe 968th Hospital of Chinese PLA, Jinzhou, Liaoning, 121000, PR China.
Tian-Le CheState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Qiang XuState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Xue-Geng HongState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Ai-Ying TengState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Shen TianState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Yuan-Yuan ZhangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Mei-Chen LiuState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Li-Ping WangDivision of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, PR China.
Simon I HayDepartment of Health Metrics Sciences, School of Medicine, University of Washington, USA.
Yang YangDepartment of Statistics, Franklin College of Arts and Sciences, University of Georgia, Athens, GA, USA.
Li-Qun FangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.
Wei LiuState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing, PR China.

Funding

ACL HHS U01CK000670
6 · The paper itself

Abstract

Background: As natural reservoirs of diverse pathogens, small mammals are considered a key interface for guarding public health due to their wide geographic distribution, high density and frequent interaction with humans. Methods: All formally recorded natural occurrences of small mammals (Order: Rodentia, Eulipotyphla, Lagomorpha, and Scandentia) and their associated microbial infections in China were searched in the English and Chinese literature spanning from 1950 to 2021 and geolocated. Machine learning models were applied to determine ecological drivers for the distributions of 45 major small mammal species and two common rodent-borne diseases (RBDs), and model-predicted potential risk locations were mapped. Findings: A total of 364 small mammal species collectively carrying 155 small mammal-associated microbes (SMAMs) combined with 215,791 human cases of eight RBDs were reported in 2484 counties in China. Murid rodents (Family: Muridae) including the brown rat ( Interpretation: The extensive intersection between small mammals and microbes with pathogenic potential in humans poses imminent threats to public health. Active field surveillance should be prioritized for potential high-risk areas identified in this study to prevent zoonotic transmission of SMAMs. Funding: National Key Research and Development Program of China; Natural Science Foundation of China; The U.S. Centers for Disease Control and Prevention.

Indexed as

RodentSmall mammalsSpatial modelling analysis

Identifiers

PMID39807372
PMCPMC11728903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.