Evidence map›Paper›PMID 39807163›Full record

ReviewiScience2025

Modeling virus filtration: Materials, applications, and mechanism.

Hironobu Shirataki, Linda Gudex, Sumith Ranil Wickramasinghe

Abstract readReview
In one paragraph

Review in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hironobu ShiratakiBioprocess Division, Asahi Kasei Medical, Tokyo 100-0006, Japan.
Linda GudexScience & Technology, Asahi Kasei Bioprocess America, Glenview, IL 60026, USA.
Sumith Ranil WickramasingheRalph E. Martin Department of Chemical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While various methods are employed to ensure the virus safety of finished products, virus filtration (VF) stands out as the preferred method for virus removal and purification of a wide variety of products owing to its capability of separating product molecules with more than 90% recovery and no change in molecule characteristics. The modeling of the virus removal process for VF membranes is based on the principles of microfiltration (MF) and ultrafiltration (UF), but with modifications for the much narrower separation difference, which is less than 2-fold for the separation of product molecules and virus particles. In this review, we introduce the materials and application of VF highlighting the unique characteristics properties of VF membranes through the steps of invention and subsequent development. We examine the virus removal mechanism and filtration models for VF to reproduce and predict the filtration behavior and virus reduction.

Indexed as

Materials applicationMaterials scienceMembranes

Identifiers

PMID39807163
PMCPMC11728907

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.