ArticleRenal failure2025
Association of geriatric nutritional risk index with renal prognosis and all-cause mortality among older patients with chronic kidney disease: a secondary analysis of CKD-ROUTE study.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Effects of home-based exercise on physical function and health-related quality of life in older patients with pre-dialysis chronic kidney disease: a single-center randomized controlled trial.Clinical and experimental nephrology · 2026Trial
- Geriatric Nutritional Risk Index and risks of all-cause, cardiovascular, and diabetes-related mortality in adults with obesity: A nationally representative cohort study.American heart journal plus : cardiology research and practice · 2026Article
- Article
- Protein Intake and Kidney Outcomes in Nondialysis Chronic Kidney Disease Over 15 Years.JAMA network open · 2026Article
- Development and Validation of a Nomogram for Predicting Chronic Kidney Disease in Older Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease.Journal of multidisciplinary healthcare · 2026Article
- Association Between Nutritional Status and Severe Sarcopenia in Maintenance Hemodialysis Patients: A Multicenter Cross-Sectional Study with Diagnostic Model Development.International journal of general medicine · 2026Article
- Mortality Risk of Sarcopenia and Malnutrition in Older Patients with Type 2 Diabetes Mellitus.Nutrients · 2025Article
- Association Between Nutritional Status and Early Postoperative Infection Risk in Kidney Transplant Patients.Nutrients · 2025Observational
- Malnutrition in Elderly Patients with Chronic Kidney Disease-The Role of Albuminuria.Life (Basel, Switzerland) · 2025Article
- Association between objective nutritional indices and malnutrition inflammation score in peritoneal dialysis patients.Frontiers in nutrition · 2025Article
- Association between geriatric nutritional risk index and fecal incontinence in individuals with stroke: mediating roles of systemic immune inflammation index and oxidative balance scores.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of the study was to assess the association between the geriatric nutritional risk index (GNRI) and incidence of CKD progression, all-cause mortality, and cardiovascular events in the elderly patients with chronic kidney disease (CKD) before dialysis initiation.
methodsWe performed a post hoc analysis of the CKD-ROUTE database, which included 538 pre-dialysis CKD patients aged ≥65 years in this prospective cohort study. Associations between GNRI and clinical outcomes were estimated using Cox proportional hazards model analysis. Multivariable linear mixed regression models with random intercepts were used to assess the association between GNRI and estimated glomerular filtration rate (eGFR) decline per year.
resultsDuring the median follow-up period of 2.92 years, there were 123 (22.86%) CKD progression events, 44 (8.18%) deaths, and 76 (14.13%) cardiovascular events. After adjusting for multiple confounding factors, the hazard ratios (HRs) for CKD progression in patients with GNRI <92 were 1.99 (95% CI, 1.34-2.97;
conclusionsThe lower GNRI is significantly associated with higher risks of renal prognosis and all-cause mortality in elderly patients with CKD.
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