ArticleBMJ open2024
Ocular biometric parameters in Chinese preschool children and physiological axial length growth prediction using machine learning algorithms: a retrospective cross-sectional study.
Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The application of artificial intelligence in myopia prediction for children and adolescents: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Mediating Role of Insulin Resistance in the Association Between Body Composition and Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Predicting myopia risk using a machine learning model based on fundus imageomics.Scientific reports · 2025Article
- Research on the predictive performance of using ROC curve to evaluate axial length for myopia in children and adolescents.BMC ophthalmology · 2025Article
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11 authors.
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Abstract
objectivesTo examine the ocular biometric parameters and predict the annual growth rate of the physiological axial length (AL) in Chinese preschool children aged 4-6 years old.
methodsThis retrospective cross-sectional study included 1090 kindergarten students (1090 right eyes) between the ages of 4 and 6 years from Pinggu and Chaoyang District, Beijing. Dioptre values were ascertained following cycloplegic autorefraction. Predicted AL was obtained through the application of the Gaussian process regression model as an optimisation technique. Subsequently, the annual growth rate of physiological AL for non-myopic preschool children (n=1061) was computed via the backward difference method.
resultsIn total, 85.4% of preschool children (931 individuals) had hyperopic refractive status in the 4-6 years age group, while only 2.7% (29 individuals) showed myopia. Boys had longer AL, larger AL-to-corneal radius ratio, deeper anterior chamber depth and lower lens power. The average physiological axial growth for boys and girls ranged from 0.050 mm/year to 0.165 mm/year and 0.063 mm/year to 0.168 mm/year, respectively. As age increased, the physiological AL growth in non-myopic cases decreased. Additionally, as hyperopic spherical equivalent refraction error lessened, the physiological AL growth component slowed down.
conclusionsIn preschool children, refractive development predominantly exhibits mild hyperopia. The concept of physiological AL provides valuable insights into the complexities of ocular development.
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