Evidence map›Paper›PMID 39806655›Full record

ArticleBMJ open2024

Efficacy and safety of various regional nerve blocks for postoperative analgesia in paediatric patients undergoing developmental dysplasia of the hip surgery: a protocol for systematic review and network meta-analysis.

Yu Zhang, Chen Fu, Wang Junxia, Lei Yang, Zhijun Qin

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu Zhang *Department of Anesthesiology, Sichuan Province Orthopedic Hospital, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0002-3659-3672
Chen Fu *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Wang JunxiaDepartment of Anesthesiology, Sichuan Urology Hospital, Chengdu, China.
Lei YangDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China yanglei.wcha@scu.edu.cn qin18716111836@126.com.ORCID http://orcid.org/0000-0003-0232-7915
Zhijun QinDepartment of Anesthesiology, Sichuan Province Orthopedic Hospital, Chengdu, Sichuan, China yanglei.wcha@scu.edu.cn qin18716111836@126.com.ORCID http://orcid.org/0000-0003-3664-090X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlleviating postoperative pain from developmental dysplasia of the hip (DDH) surgery is beneficial for paediatric patients. The most commonly used anaesthetic approach currently is general anaesthesia combined with regional nerve blocks. Existing research primarily focuses on studies comparing regional nerve blocks with placebo controls, or studies comparing two different regional nerve blocking techniques. However, the conclusions from these studies offer limited assistance to clinicians in selecting the safest and most effective nerve block. Therefore, we plan to conduct a systematic review and network meta-analysis to compare the efficacy and safety of different regional nerve blocks in managing postoperative pain in children undergoing surgery for DDH. METHODS AND ANALYSIS: We will systematically search the following databases: MEDLINE, Embase, Cochrane Central Register of Controlled Trials via Ovid, as well as the Chinese databases CNKI and Wanfang. We will comprehensively search from the inception of each database to April 2024 and will include randomised controlled trials without restrictions on language or publication status. The primary outcome are postoperative pain scores at 4 hours following surgery. The quality of all included trials will be assessed using version 2 of the Cochrane Randomised Trial Risk of Bias Tool. We will employ the GeMTC package in R software for both direct and indirect comparisons within a Bayesian framework using a random effects model. Additionally, the Confidence in Network Meta-Analysis method will be employed to assess the quality of evidence. ETHICS AND DISSEMINATION: Ethical approval is not required for this study, as it exclusively involves the compilation of published data. We plan to submit our review to academic conferences and peer-reviewed scholarly journals. PROSPERO REGISTRATION NUMBER: CRD42024527459.

Indexed as

AnalgesiaDevelopmental Dysplasia of the HipNerve BlockPostoperative PainChildHumansNetwork Meta-Analysis as TopicRandomized Controlled Trials as TopicResearch DesignSystematic Reviews as TopicAnaesthesia in orthopaedicsPaediatric anaesthesiaPain management

Identifiers

PMID39806655
PMCPMC11667397

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.