Evidence map›Paper›PMID 39806625›Full record

ArticleBMJ open2024

Economic burden of acute kidney injury in children and adults: a protocol for a systematic review and meta-analysis.

Emma Heydari Ulrich, Aspen Lillywhite, Rashid Alobaidi, Catherine Morgan, Michael Paulden, Michael Zappitelli, Sean M Bagshaw

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma Heydari UlrichPediatrics, University of Alberta, Edmonton, Alberta, Canada.ORCID http://orcid.org/0000-0002-1619-4044
Aspen LillywhiteFaculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Rashid AlobaidiPediatrics, University of Alberta, Edmonton, Alberta, Canada.
Catherine MorganPediatrics, University of Alberta, Edmonton, Alberta, Canada.
Michael PauldenUniversity of Alberta, Edmonton, Alberta, Canada.
Michael ZappitelliPediatrics, University of Toronto, Toronto, Ontario, Canada.
Sean M BagshawDepartment of Critical Care Medicine, University of Alberta, Edmonton, Alberta, Canada bagshaw@ualberta.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute kidney injury (AKI) is common in hospitalised adults and children and is associated with significantly increased mortality and worse short-term and long-term outcomes. This systematic review and meta-analysis will evaluate the cost associated with AKI. METHODS AND ANALYSIS: This health economic analysis will be performed using systematic search of databases, including MEDLINE, EMBASE, CINAHL, Scopus and Cochrane Library from 2009 to the present (search completed on 27 May 2024). Two reviewers will independently complete study selection, data extraction and bias assessment. Inclusion criteria will be randomised controlled trials (RCTs) and observational studies (cohort or case-control) from all countries of hospitalised adults and children. The exposure will be AKI based on definitions using serum creatinine and/or urine output criteria, relative to patients without AKI. The primary outcome studied will be the cost of index hospitalisation associated with AKI episode. Other secondary outcomes will include the cost of intensive care unit admission during index hospitalisation, direct costs related to inpatient and outpatient care) and indirect (time) costs related to loss of productivity. Pooled random-effect meta-analysis ORs with 95% CIs will be reported. ETHICS AND DISSEMINATION: Ethics approval was not required due to study methodology. The authors have no competing interests to report. The results will be disseminated in peer-reviewed publications according to guidelines by the Cochrane and Centre for Reviews and Dissemination. PROSPERO REGISTRATION NUMBER: CRD42024512658.

Indexed as

Acute Kidney InjuryCost of IllnessHealth Care CostsHospitalizationAdultChildHumansMeta-Analysis as TopicResearch DesignSystematic Reviews as TopicAcute renal failureHEALTH ECONOMICSNEPHROLOGYSystematic Review

Identifiers

PMID39806625
PMCPMC11667453

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.