Evidence map›Paper›PMID 39806514›Full record

ArticleJournal of eating disorders2025

Efficacy of the ECHOMANTRA online intervention to support recovery from anorexia nervosa in adult patients: study protocol of a randomized controlled multi-center trial.

Yolanda Quiles, Álvaro Ruiz, Eva León-Zarceño, Javier Manchón, Marie-Carmen Neipp, Sofía Payá-López, Katina Kovacheva, Valentina Cardi

Abstract read
In one paragraph

Article in Journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yolanda QuilesDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández University, Avda de la Universidad S/N C. P., 03202, Elche, Spain. y.quiles@umh.es.
Álvaro RuizDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández University, Avda de la Universidad S/N C. P., 03202, Elche, Spain. alvaro.ruiz@umh.es.
Eva León-ZarceñoDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández University, Avda de la Universidad S/N C. P., 03202, Elche, Spain.
Javier ManchónDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández University, Avda de la Universidad S/N C. P., 03202, Elche, Spain.
Marie-Carmen NeippDepartment of Health Psychology, Miguel Hernández University, Elche, Spain.
Sofía Payá-LópezDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández University, Avda de la Universidad S/N C. P., 03202, Elche, Spain.
Katina KovachevaDepartment of Behavioral Sciences and Health, Edificio Altamira, Miguel Hernández University, Avda de la Universidad S/N C. P., 03202, Elche, Spain.
Valentina CardiDipartamento di Psicologia Generale, Università degli Studi di Padova, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor quality of life in adults with anorexia nervosa (AN) and persistent high rates of readmission highlight the necessity of developing interventions to optimize treatment outcomes. ECHOMANTRA is a novel online intervention based on interventions for carers (Experienced Carers Helping Others, ECHO) and patients (Maudsley Model of Anorexia Nervosa Treatment for Adults, MANTRA) with anorexia nervosa. The objective of this paper is to describe the study protocol of a randomized control trial (RCT) aimed at evaluating the efficacy of an adaptation of the ECHOMANTRA for adults AN inpatients and outpatients, and their carers, to be implemented as an add-on to treatment-as-usual (TAU).

methodsIn a multi - center pilot randomized controlled trial (RCT), 148 adult AN patients, and their carers, will be randomized to receive treatment as usual (TAU) or TAU plus ECHOMANTRA. Assessments will take place at baseline (T0), post-intervention (2-month) (T1), 6-month follow-up (T2), and 12-month follow-up (T3). Primary outcomes will be eating disorder psychopathology and psychological well-being. For carers, outcome variables will include psychological well-being, accommodation and enabling behaviors, expressed emotion, illness burden, quality of life and care skills. DISCUSSION: This study will provide evidence of the efficacy of this novel, online and protocolized intervention in facilitating the recovery of these patients.

trial registrationISRCTN registry (Identifier: 80253157 https://doi.org/10.1186/ISRCTN80253157 ).

Indexed as

AdultAnorexia nervosaECHOMANTRARCTTreatment

Identifiers

PMID39806514
PMCPMC11731152

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.