Evidence map›Paper›PMID 39806509›Full record

ArticleVeterinary research2025

CRISPR/Cas9-editing of PRNP in Alpine goats.

Aurélie Allais-Bonnet, Christophe Richard, Marjolaine André, Valérie Gelin, Marie-Christine Deloche, Aurore Lamadon, Gwendoline Morin, Béatrice Mandon-Pépin, Eugénie Canon, Dominique Thépot and 10 more

Abstract read
In one paragraph

Article in Veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Aurélie Allais-Bonnet *Eliance, Paris, France.
Christophe Richard *UVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Marjolaine AndréUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Valérie GelinUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Marie-Christine DelocheEliance, Paris, France.
Aurore LamadonUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Gwendoline MorinINRAE, SAJ, 78350, Jouy-en-Josas, France.
Béatrice Mandon-PépinUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Eugénie CanonUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Dominique ThépotUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Johann LaubierINRAE, AgroParisTech, GABI, Université Paris-Saclay, Jouy-en-Josas, France.
Katayoun Moazami-GoudarziINRAE, AgroParisTech, GABI, Université Paris-Saclay, Jouy-en-Josas, France.
Ludivine LaffontUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Olivier DuboisUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France.
Thierry FassierINRAE, UE P3R Bourges, Domaine de Bourges, 31326, Osmoy, France.
Patrice CongarINRAE, SAJ, 78350, Jouy-en-Josas, France.
Olivier LasserreINRAE, PAO, Nouzilly, France.
Tiphaine Aguirre-LavinINRAE, PAO, Nouzilly, France.
Jean-Luc VilotteINRAE, AgroParisTech, GABI, Université Paris-Saclay, Jouy-en-Josas, France.
Eric PailhouxUVSQ, INRAE, BREED, Université Paris-Saclay, 78350, Jouy-en-Josas, France. eric.pailhoux@inrae.fr.ORCID http://orcid.org/0000-0001-8012-9143

Funding

Horizon 2020 Framework Programme 101000226
6 · The paper itself

Abstract

Misfolding of the cellular PrP (PrP

Indexed as

CRISPR-Cas SystemsGene EditingGoat DiseasesGoatsPrion ProteinsPrionsAnimalsFemaleGene Knockout TechniquesMalePrion DiseasesPrion ProteinsPrionsanimal healthembryo editinggoatknockoutPRION proteinPRNP gene

Identifiers

PMID39806509
PMCPMC11731167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.