Evidence map›Paper›PMID 39806310›Full record

ArticleAnnals of clinical microbiology and antimicrobials2025

Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching hospitals.

Pengyu Zhang, Jingchen Hao, Yafen Zhang, Junfeng Su, Guozhuang Sun, Jun Xie, Jian Hu, Guocai Li

Abstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Convergent Architecture of thePathogens (Basel, Switzerland) · 2026
    Article
  2. Convergent evolution of ST2 and ST164 mediates dissemination of the blaAnnals of clinical microbiology and antimicrobials · 2026
    Article
  3. Article
  4. Whole-Genome Sequencing of Multidrug-ResistantInternational journal of molecular sciences · 2026
    Article
  5. Review
  6. Molecular analysis of carbapenem-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  7. Clonal Diversity and Resistome Dynamics ofMedicina (Kaunas, Lithuania) · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pengyu Zhang *Department of Microbiology, Medical College, Yangzhou University, Yangzhou, 225001, China.
Jingchen Hao *Department of Microbiology, Medical College, Yangzhou University, Yangzhou, 225001, China.
Yafen ZhangDepartment of Laboratory Medicine, Affiliated Hospital of Yangzhou University, Yangzhou, 225001, PR China.
Junfeng SuDepartment of Microbiology, Medical College, Yangzhou University, Yangzhou, 225001, China.
Guozhuang SunDepartment of Laboratory Medicine, Xuyi County People's Hospital / Clinical College, Yangzhou University, Yangzhou, 211799, China.
Jun XieDepartment of Laboratory Medicine, Xuyi County People's Hospital / Clinical College, Yangzhou University, Yangzhou, 211799, China.
Jian HuDepartment of Laboratory Medicine, Guangling College / Clinical College, Yixing Hospital of Traditional Chinese Medicine, Yangzhou University, Yangzhou, 214200, China. yxszyyy795@163.com.
Guocai LiDepartment of Microbiology, Medical College, Yangzhou University, Yangzhou, 225001, China. gcli@yzu.edu.cn.

Funding

Jiangsu Provincial Natural Science Foundation of China BK20231241National Natural Science Foundation of China 82373637
6 · The paper itself

Abstract

backgroundCarbapenem-resistant Acinetobacter baumannii (CRAB) is recognized as a common clinical conditional pathogen with bla

methodsWe conducted a retrospective study of CRAB patients at three teaching hospitals from 2019 to 2022. We identified bacterial isolates, collected clinical data, and performed antimicrobial susceptibility testing. Genome characteristics of isolates were investigated by whole genome sequencing. Multilocus sequence typing and phylogenetic trees were used to assess the genetic similarity of isolates. Acquired antimicrobial resistance genes and virulence factors carried in the isolated group genome were analyzed by ResFinder, PubMLST and VFDB. Sequence alignment was used to analyze genetic environment around bla

resultsA total of 92 non-repetitive CRAB isolates were collected, with sputum samples accounting for the majority (94.57%, n = 87) of samples. These were distributed into ST2, with ST2 identified to have the highest prevalence of infection, accounting for 99.99% (n = 91) of all isolates. The major resistance genes identified were bla

conclusionsWe find that CRAB is prevalent within the ICU and is progressively resistant to antibiotics over time. Enhanced clinical understanding and timely management of CRAB infections will be crucial to minimize or even eliminate the spread of CRAB within the ICU setting.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsCarbapenemsAdultAgedbeta-LactamasesDrug Resistance, Multiple, BacterialFemaleGenome, BacterialHospitals, TeachingHumansIntensive Care UnitsMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial Agentsbeta-LactamasesCarbapenemsVirulence Factors

Identifiers

PMID39806310
PMCPMC11731405

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.