Evidence map›Paper›PMID 39806295›Full record

ArticleBMC bioinformatics2025

Solu: a cloud platform for real-time genomic pathogen surveillance.

Timo Saratto, Kerkko Visuri, Jonatan Lehtinen, Irene Ortega-Sanz, Jacob L Steenwyk, Samuel Sihvonen

Abstract read
In one paragraph

Article in BMC bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Emergence ofASM case reports · 2026
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A comparative review of three cloud-based platforms for microbial whole genome sequencing analysis.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  11. Article
  12. Article
  13. Genomic characterization ofFrontiers in veterinary science · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Timo SarattoSolu Healthcare Oy, Kalevankatu 31 A 13, 00100, Helsinki, Finland. timo@solugenomics.com.
Kerkko VisuriSolu Healthcare Oy, Kalevankatu 31 A 13, 00100, Helsinki, Finland.
Jonatan LehtinenSolu Healthcare Oy, Kalevankatu 31 A 13, 00100, Helsinki, Finland.
Irene Ortega-SanzDepartment of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000, Ghent, Belgium.
Jacob L SteenwykHowards Hughes Medical Institute and the Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
Samuel SihvonenSolu Healthcare Oy, Kalevankatu 31 A 13, 00100, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGenomic surveillance is extensively used for tracking public health outbreaks and healthcare-associated pathogens. Despite advancements in bioinformatics pipelines, there are still significant challenges in terms of infrastructure, expertise, and security when it comes to continuous surveillance. The existing pipelines often require the user to set up and manage their own infrastructure and are not designed for continuous surveillance that demands integration of new and regularly generated sequencing data with previous analyses. Additionally, academic projects often do not meet the privacy requirements of healthcare providers.

resultsWe present Solu, a cloud-based platform that integrates genomic data into a real-time, privacy-focused surveillance system. EVALUATION: Solu's accuracy for taxonomy assignment, antimicrobial resistance genes, and phylogenetics was comparable to established pathogen surveillance pipelines. In some cases, Solu identified antimicrobial resistance genes that were previously undetected. Together, these findings demonstrate the efficacy of our platform.

conclusionsBy enabling reliable, user-friendly, and privacy-focused genomic surveillance, Solu has the potential to bridge the gap between cutting-edge research and practical, widespread application in healthcare settings. The platform is available for free academic use at https://platform.solugenomics.com .

Indexed as

Cloud ComputingGenomicsSoftwareHumansPhylogenyGenomicsInfection preventionOutbreakPhylogenyPrivacyWhole-genome sequencingWorkflow

Identifiers

PMID39806295
PMCPMC11731562

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.