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ArticleNeurosurgical review2025

Hemispheric asymmetry and its influence on cranioplasty complications after decompressive craniectomy.

Francesco M C Lioi, Alessandro Frati, Jon Ramm-Pettersen, Gabriele Dentato, Andrea Fratini, Luigi Rosito, Camilla Riva, Niccolo Colella, Pietro Familiari, Antonio Santoro and 1 more

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Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco M C LioiDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy. lioifrancesco@gmail.com.ORCID https://orcid.org/0009-0005-5462-8818
Alessandro FratiDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Jon Ramm-PettersenDepartment of Neurosurgery, Oslo University Hospital, Oslo, 0407, Norway.
Gabriele DentatoDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Andrea FratiniDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Luigi RositoDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Camilla RivaDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Niccolo ColellaDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Pietro FamiliariDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Antonio SantoroDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
Paolo MissoriDepartment of Neurosurgery, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore temporal dynamics of cerebral herniation through the calvarial defect after decompressive craniectomy. To investigate patterns of hemispheric asymmetry in ischemic stroke and traumatic brain injury after decompressive craniectomy.To assess clinical implications of hemispheric asymmetry evaluation in order to minimize cranioplasty complications. Using a CT semiautomatic segmentation system, the ipsilateral and contralateral hemispheric areas of patients who underwent decompressive craniectomy for malignant ischemic stroke and traumatic brain injury were measured during the acute (1-7 days), subacute (8-21 days) and chronic (over 21 days) periods. Difference between the two hemispheric areas, called hemispheric asymmetry, has been investigated. Of the 53 patients, 38 (71.7%) had a malignant ischemic stroke, and 15 (28.3%) had a severe head brain injury. In stroke, a significant increase in hemispheric asymmetry was found during acute and subacute phases (+ 6.7 ± 5.1 cm

Indexed as

Brain Injuries, TraumaticDecompressive CraniectomyIschemic StrokePostoperative ComplicationsSkullAdultAgedEncephaloceleFemaleHumansMaleMiddle AgedTomography, X-Ray ComputedBrain swellingCranioplastyDecompressive craniectomyHead injuryIschemic stroke

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.