Evidence map›Paper›PMID 39805963›Full record

ArticleEye (London, England)2025

Anatomical and functional results of patients with late-stage age-related macular degeneration 6 months after smaller-incision new-generation implantable miniature telescope (SING IMT™) implantation.

Ginevra Giovanna Adamo, Marco Pellegrini, Francesco Nasini, Pietro Maria Talli, Laura Sarti, Piera Perri, Francesco Parmeggiani, Marco Mura

Abstract read
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ginevra Giovanna AdamoDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy. aginevra3@gmail.com.ORCID 0009-0001-9417-1200
Marco PellegriniDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Francesco NasiniSant'Anna University Hospital, Ferrara, Italy.
Pietro Maria TalliSant'Anna University Hospital, Ferrara, Italy.ORCID 0000-0002-7428-4531
Laura SartiDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Piera PerriSant'Anna University Hospital, Ferrara, Italy.
Francesco ParmeggianiDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Marco MuraDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to evaluate anatomical and functional outcomes of the Smaller-Incision New Generation Implantable Miniature Telescope (SING IMT™) in patients with bilateral advanced age-related macular degeneration (AMD).

methodsThis non-comparative retrospective single-surgeon interventional case series included patients with bilateral late-stage AMD who underwent cataract surgery and SING IMT™ implantation at the Sant'Anna University Hospital, University of Ferrara, Italy. The main outcome measures included corrected distance (CDVA) and near visual acuity (CNVA), endothelial cell loss (ECL), and incidence of complications.

results11 eyes of 11 patients were included. The mean follow-up duration was 6.5 ± 2.4 months. After surgery, CDVA significantly improved (from 17.00 ± 9.74 to 26.00 ± 8.53) letters (P = 0.008). Significant improvement of CNVA was also observed (from 12.27 ± 4.36 to 8 ± 2.61 Jaeger levels; P = 0.004). Mean ECL was 4.8 ± 5.5% at 3 months. No intraoperative complications were observed, while postoperative complications included iris incarceration (9.1%), pigment deposition on the device (9.1%), and transient corneal oedema (27.3%). Nevertheless, 10 of 11 patients (90.9%) began to complain of blurred or hazy vision within 3 months of surgery. The device was ultimately explanted in 3 patients (27.3%) because of this symptom.

conclusionsAlthough SING IMT™ implantation is associated with promising objective results, unexplained blurred or hazy vision represents common postoperative complaints which may lead to patient dissatisfaction. Further studies including patient-reported outcomes are warranted to evaluate the effect of the intervention on patients' visual function and quality of life.

Indexed as

Macular DegenerationProsthesis ImplantationAgedAged, 80 and overCorneal Endothelial Cell LossFemaleFollow-Up StudiesHumansMaleMiddle AgedPhacoemulsificationPostoperative ComplicationsRetrospective StudiesTreatment OutcomeVisual Acuity

Identifiers

PMID39805963
PMCPMC11794482

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