ArticleAJNR. American journal of neuroradiology2025
Peritumoral Hyperintense Signal on Postcontrast FLAIR Images Surrounding Vestibular Schwannomas following Stereotactic Radiosurgery.
Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
background and purposePrior investigations have noted the presence of peritumoral hyperintense signal (a "halo") around vestibular schwannomas on postcontrast 3D T2 FLAIR images. This study evaluated this phenomenon in a cohort of patients undergoing stereotactic radiosurgery. MATERIALS AND
methodsA retrospective review was completed of consecutive patients with presumed vestibular schwannomas undergoing stereotactic radiosurgery. Tumor size, location, presence or absence of a peritumoral halo, and halo thickness were recorded. Images were reviewed for presence and size of peritumoral hyperintense signal on postcontrast 3D T2 FLAIR images before and after treatment.
resultsTwenty-six patients were included in this study, 14 of whom were women (54.0%). Average age was 62 ± 12 years. Before treatment, a postcontrast 3D T2 FLAIR hyperintense peritumoral halo was seen in 85% of patients, averaging 0.8 ± 0.4 mm in thickness. There was a higher incidence of peritumoral halo in posttreatment patients (96%) than pretreatment patients (85%) (
conclusionsVestibular schwannomas treated with stereotactic radiosurgery are more likely to have a peritumoral halo on postcontrast 3D T2 FLAIR images, with larger halo size as compared with pretreatment studies. Further study with a larger tumor cohort and longer follow-up will be necessary to determine if these findings are predictive of subsequent tumor shrinkage.
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