Evidence map›Paper›PMID 39805516›Full record

Trial reportChest2025

Video vs Direct Laryngoscopy for Tracheal Intubation After Cardiac Arrest: A Secondary Analysis of the Direct vs Video Laryngoscope Trial.

Amelia L Muhs, Kevin P Seitz, Edward T Qian, Brant Imhoff, Li Wang, Matthew E Prekker, Brian E Driver, Stacy A Trent, Daniel Resnick-Ault, Steven G Schauer and 34 more

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Chest, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Amelia L MuhsDivision of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN. Electronic address: amelia.muhs@vumc.org.
Kevin P SeitzDivision of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.
Edward T QianDivision of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.
Brant ImhoffDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.
Li WangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.
Matthew E PrekkerDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hennepin County Medical Center, Minneapolis, MN; Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, MN.
Brian E DriverDepartment of Emergency Medicine, Hennepin County Medical Center, Minneapolis, MN.
Stacy A TrentDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Daniel Resnick-AultDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Steven G SchauerDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Adit A GindeDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Derek W RussellDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL.
Sheetal GandotraDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL.
David B PageDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL.
John P GaillardDepartment of Emergency Medicine, Wake Forest University School of Medicine, Winston-Salem.
Lane M SmithDepartment of Emergency Medicine, Wake Forest University School of Medicine, Winston-Salem.
Andrew J LatimerDepartment of Emergency Medicine, University of Washington Harborview Medical Center, University of Washington, Seattle, WA.
Steven H MitchellDepartment of Emergency Medicine, University of Washington Harborview Medical Center, University of Washington, Seattle, WA.
Nicholas J JohnsonDepartment of Emergency Medicine, University of Washington Harborview Medical Center, University of Washington, Seattle, WA; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA.
Shekhar A GhamandeDivision of Pulmonary and Critical Care Medicine, Baylor Scott & White Healthcare, Temple, TX.
Heath D WhiteDivision of Pulmonary and Critical Care Medicine, Baylor Scott & White Healthcare, Temple, TX.
Kevin W GibbsDivision of Pulmonary, Critical Care, Allergy, and Immunology, Wake Forest University School of Medicine, Winston-Salem.
Jessica A PalakshappaDivision of Pulmonary, Critical Care, Allergy, and Immunology, Wake Forest University School of Medicine, Winston-Salem.
Derek J VonderhaarDivision of Pulmonary and Critical Care Medicine, Ochsner Medical Center, LSU School of Medicine New Orleans, New Orleans, LA.
David R JanzDivision of Pulmonary and Critical Care Medicine, LSU School of Medicine New Orleans, New Orleans, LA.
Micah R WhitsonDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL; Department of Emergency Medicine, University of Alabama at Birmingham, Birmingham, AL.
Christopher R BarnesDepartment of Anesthesiology and Critical Care Medicine, University of Washington Harborview Medical Center, University of Washington, Seattle, WA.
Alon DaganDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA.
Ari MoskowitzDivision of Critical Care Medicine, Montefiore Medical Center, The Bronx, NY.
Vijay KrishnamoorthyDepartment of Anesthesiology, Duke University School of Medicine, Durham, NC.
James T HerbertDepartment of Anesthesiology, Duke University School of Medicine, Durham, NC.
Michael D AprilUniformed Services University of the Health Sciences, Bethesda, MD; 14th Field Hospital, Fort Stewart, GA.
Aaron M JoffeDepartment of Anesthesiology, Creighton University School of Medicine, Omaha, NE.
Jeremy P WalcoDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.
Christopher G HughesDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.
Kipp ShipleyDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.
Amelia W MaigaDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN.
Bradley D LloydDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN.
Stephanie C DeMasiDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN.
Wesley H SelfDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN.
Todd W RiceDivision of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.
Matthew W SemlerDivision of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.
Jonathan D CaseyDivision of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.
Pragmatic Critical Care Research Group

Funding

Activated Neutrophilic Exosome as Biomarker and Therapeutic Target in COPDK08HL148514 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RUSSELL, DEREK · 2020 to 2024
$824k
NHLBI NIH HHS K08 HL148514
6 · The paper itself

Abstract

backgroundAirway management is a critical component of the care of patients experiencing cardiac arrest, but data from randomized trials on the use of video vs direct laryngoscopy for intubation in the setting of cardiac arrest are limited. Current American Heart Association guidelines recommend placement of an endotracheal tube either during CPR or shortly after return of spontaneous circulation, but do not provide guidance around intubation methods, including the choice of laryngoscope. RESEARCH QUESTION: Does use of video laryngoscopy improve the incidence of successful intubation on the first attempt, compared with use of direct laryngoscopy, among adults undergoing tracheal intubation after experiencing cardiac arrest? STUDY DESIGN AND

methodsThis secondary analysis of the Direct vs Video Laryngoscope (DEVICE) trial compared video laryngoscopy vs direct laryngoscopy in the subgroup of patients who were intubated after cardiac arrest. The primary outcome was the incidence of successful intubation on the first attempt. Additional outcomes included the duration of laryngoscopy.

resultsAmong the 1,417 patients in the DEVICE trial, 113 patients (7.9%) experienced cardiac arrest before intubation, of whom 48 patients were randomized to the video laryngoscopy group and 65 patients were randomized to the direct laryngoscopy group. Successful intubation on the first attempt occurred in 40 of 48 patients (83.3%) in the video laryngoscopy group and in 42 of 65 patients (64.6%) in the direct laryngoscopy group (absolute risk difference, 18.7 percentage points; 95% CI, 1.2-36.2 percentage points; P = .03). The mean duration of laryngoscopy was 48.0 seconds (SD, 37.3 seconds) in the video laryngoscope group and 98.0 seconds (SD, 122.4 seconds) in the direct laryngoscopy group (mean difference, -50.0 seconds; 95% CI, -86.8 to -13.3 seconds; P = .004).

interpretationAmong adults undergoing tracheal intubation after experiencing cardiac arrest, use of video laryngoscopy was associated with increased incidence of successful intubation on the first attempt and shortened duration of laryngoscopy, compared with use of direct laryngoscopy.

Indexed as

Cardiopulmonary ResuscitationHeart ArrestIntubation, IntratrachealLaryngoscopesLaryngoscopyVideo-Assisted Techniques and ProceduresAgedFemaleHumansMaleMiddle AgedVideo Recordingcardiac arrestdirect laryngoscopyintubationvideo laryngoscopy

Identifiers

PMID39805516
PMCPMC12106960

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.