Evidence map›Paper›PMID 39804984›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Spatiotemporal Dynamic Immunomodulation by Infection-Mimicking Gels Enhances Broad and Durable Protective Immunity Against Heterologous Viruses.

Seung Mo Jin, Ju Hee Cho, Yebin Seong, Wijesinghe Arachchilage Gayan Chathuranga, Yejin Gwak, Young-Woock Noh, Min-Ho Lee, Sang-Seok Oh, Jin-Ho Choi, Jong-Soo Lee and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Microorganisms · 2026
    Article
  2. Microorganisms · 2026
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Seung Mo JinSKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, Department of Nano Science and Technology, School of Chemical Engineering, Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Ju Hee ChoSKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, Department of Nano Science and Technology, School of Chemical Engineering, Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Yebin SeongCollege of Veterinary Medicine, Chungnam National University, Daejeon, 34134, Republic of Korea.
Wijesinghe Arachchilage Gayan ChathurangaCollege of Veterinary Medicine, Chungnam National University, Daejeon, 34134, Republic of Korea.
Yejin GwakSKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, Department of Nano Science and Technology, School of Chemical Engineering, Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Young-Woock NohNew Drug Development Center, Osong Medical Innovation Foundation, Cheongju, 28160, Republic of Korea.
Min-Ho LeeNew Drug Development Center, Osong Medical Innovation Foundation, Cheongju, 28160, Republic of Korea.ORCID https://orcid.org/0000-0003-0197-3456
Sang-Seok OhNew Drug Development Center, Osong Medical Innovation Foundation, Cheongju, 28160, Republic of Korea.ORCID https://orcid.org/0009-0001-7321-0338
Jin-Ho ChoiSKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, Department of Nano Science and Technology, School of Chemical Engineering, Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea.
Jong-Soo LeeCollege of Veterinary Medicine, Chungnam National University, Daejeon, 34134, Republic of Korea.
Yong Taik LimSKKU Advanced Institute of Nanotechnology (SAINT), Department of Nano Engineering, Department of Nano Science and Technology, School of Chemical Engineering, Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea.ORCID https://orcid.org/0000-0001-5558-5526

Funding

National Research Foundation 2021R1A6A1A03045495National Research Foundation NRF-2020R1A2C3006888National Research Foundation RS-2023-00218648
6 · The paper itself

Abstract

Despite their safety and widespread use, conventional protein antigen-based subunit vaccines face significant challenges such as low immunogenicity, insufficient long-term immunity, poor CD8

Indexed as

COVID-19COVID-19 VaccinesImmunomodulationAnimalsFemaleGelsHumansMiceNanoparticlesSARS-CoV-2COVID-19 VaccinesGelsadjuvantdrug deliveryimmunomodulationinfluenzananovaccineSARS‐CoV‐2

Identifiers

PMID39804984
PMCPMC11884557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.