Evidence map›Paper›PMID 39804498›Full record

Observational studyArchives of dermatological research2025

Prediction of treatment efficacy in psoriasis vulgaris using dermoscopic and capillaroscopic findings: a prospective cohort study.

Muhammet Resat Akkus, Kemal Ozyurt, Mustafa Atasoy, Ragip Ertas, Huzeyfe Kulu, Sinem Sogancioglu Ozata, Abdullah Demirbas, Omer Faruk Elmas, Esin Diremsizoglu

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muhammet Resat AkkusMehmet Akif Inan Training and Research Hospital, Department of Dermatology, Sanlıurfa, Türkiye.
Kemal OzyurtAcıbadem Kayseri Hospital, Department of Dermatology, Kayseri, Türkiye.
Mustafa AtasoyMemorial Atasehir Hospital, Department of Dermatology, Istanbul, Türkiye.
Ragip ErtasMedical Palace Hospital, Department of Dermatology, Kayseri, Türkiye.
Huzeyfe KuluAksaray Training and Research Hospital, Department of Dermatology, Aksaray, Türkiye.
Sinem Sogancioglu OzataZile Public Hospital, Department of Dermatology, Tokat, Türkiye.
Abdullah DemirbasDepartment of Dermatology, Kocaeli University Faculty of Medicine, Kocaeli, Türkiye.
Omer Faruk ElmasInternational Medicana Hospital, Department of Dermatology, Istanbul, Türkiye.
Esin DiremsizogluDepartment of Dermatology, Kocaeli University Faculty of Medicine, Kocaeli, Türkiye. mdesinarslan@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPsoriasis is a chronic inflammatory skin disorder affecting millions worldwide. Dermoscopy and proximal nailfold capillaroscopy have emerged as valuable tools for understanding the pathophysiology and treatment response of psoriasis lesions.

objectivesThis study aimed to contribute to the limited literature on using dermoscopic findings to detect treatment effectiveness in patients with psoriasis vulgaris.

methodsThis prospective, single-blinded, observational cohort study included 101 patients aged 18-71 years diagnosed with psoriasis vulgaris who initiated or altered systemic treatment. Monthly dermoscopic and capillaroscopic evaluations were performed alongside assessments of Psoriasis Area Severity Index (PASI), Body Surface Area (BSA), and Dermatology Life Quality Index (DLQI) scores.

resultsA significant relationship was found between first-month dermoscopic findings and third-month severity scores (PASI, BSA, DLQI). Patients with positive treatment responses exhibited changes from baseline regular capillary dilations to hemorrhagic spots or the absence of vascular findings during the first month. The correlations between dermoscopic changes and severity scores evolved over time, becoming stronger in the second and third months. Nailfold capillaroscopy findings at the third month of treatment showed significant differences from baseline.

conclusionsDermoscopy is a fast, practical, and inexpensive tool for early prediction of treatment effectiveness in psoriasis vulgaris. The disappearance of regular capillary dilations or their change to hemorrhagic spots suggests treatment efficacy, while their persistence indicates poor treatment response. Early detection of treatment effectiveness using dermoscopic findings can facilitate timely adjustments, improving patient outcomes and reducing unnecessary treatment exposure.

Indexed as

DermoscopyMicroscopic AngioscopyPsoriasisAdolescentAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeSeverity of Illness IndexSingle-Blind MethodTreatment OutcomeYoung AdultCapillaroscopyDermoscopyMicrocirculationPsoriasis vulgarisTreatment efficacy

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.