Evidence map›Paper›PMID 39804495›Full record

ArticleMikrochimica acta2025

Dye-sensitized upconversion nanoprobes with ultra-high signal-to-background ratio for visual and sensitive detection of nerve agent mimics.

Shushu Zhou, Zhenhua Liu, Xueyu Peng, Dailiang Zhang, Minghui Yang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shushu ZhouHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China.
Zhenhua LiuHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China.
Xueyu PengSansure Biotech Inc, Changsha, 410205, China.
Dailiang ZhangHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China. zhangdl22@csu.edu.cn.
Minghui YangHunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China. yangminghui@csu.edu.cn.

Funding

Central South University 2024ZZTS0327National Natural Science Foundation of China 22174163National Natural Science Foundation of China 22304189Natural Science Foundation of Hunan Province 2023JJ70059
6 · The paper itself

Abstract

An exciting upconversion nanoprobe conditioning strategy is proposed to improve the signal-to-background ratio (SBR) through a dye-sensitized strategy, in which the dye functions both as a recognition unit of the detection target and as a sensitizer to amplify the visible luminescence of the lanthanide-doped upconversion nanoparticles (UCNPs), instead of a quencher. The application of this dye-sensitized upconversion nanoprobe to the visual detection of nerve agent mimics diethoxy phosphatidylcholine (DCP) showed excellent detection performance, with up to 110-fold enhancement of the luminescence response of the probe in DCP solution and a detection limit as low as 2 nM. Finally, we performed visual detection of DCP solution and vapor by using test strips containing the probe. It is promising to apply the probe to monitor the leakage of DCP in the real environment.

Indexed as

Dye sensitizationNerve agent mimicsUpconversion nanoparticlesVisual detection

Identifiers

PMID39804495

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.