Evidence map›Paper›PMID 39804493›Full record

ArticleRheumatology international2025

Coronary artery calcification progression and renal involvement in patients with systemic lupus erythematosus: a longitudinal cohort study.

Lise Zinglersen, Amanda Hempel Zinglersen, Katrine Aagaard Myhr, Marie-Louise Hermansen, Klaus Fuglsang Kofoed, Andreas Fuchs, Louise P Diederichsen, Søren Jacobsen

Abstract read
In one paragraph

Article in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lise ZinglersenCopenhagen Research Center for Autoimmune Connective Tissue Diseases (COPEACT), Copenhagen University Hospital, Rigshospitalet, Denmark. Lise.zinglersen.01@regionh.dk.ORCID 0000-0002-1816-6418
Amanda Hempel ZinglersenCopenhagen Research Center for Autoimmune Connective Tissue Diseases (COPEACT), Copenhagen University Hospital, Rigshospitalet, Denmark.ORCID 0000-0003-2880-1638
Katrine Aagaard MyhrDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, Denmark.ORCID 0000-0003-0838-0987
Marie-Louise HermansenDiagnostic Centre, Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-9108-8604
Klaus Fuglsang KofoedDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, Denmark.ORCID 0000-0001-9742-1554
Andreas FuchsDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, Denmark.ORCID 0000-0003-0236-0811
Louise P DiederichsenCopenhagen Research Center for Autoimmune Connective Tissue Diseases (COPEACT), Copenhagen University Hospital, Rigshospitalet, Denmark.ORCID 0000-0002-2581-8912
Søren JacobsenCopenhagen Research Center for Autoimmune Connective Tissue Diseases (COPEACT), Copenhagen University Hospital, Rigshospitalet, Denmark.ORCID 0000-0002-5654-4993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate if progression of coronary artery calcification (CAC) in patients with systemic lupus erythematosus (SLE) is associated with renal and traditional cardiovascular risk factors as well as incidence of myocardial infarctions. CAC progression was evaluated by cardiac computed tomography (CT) at baseline and after 5 years. Multivariable Poisson regression was applied to investigate associations between CAC progression and baseline values for traditional cardiovascular risk factors, CAC, SLE disease duration, lupus nephritis, and renal function. Regarding renal function, three groups were defined based on eGFR. Further, we analysed association between CAC progression and myocardial infarction during follow-up. Of the 147 SLE patients, 99 had cardiac CT at baseline and 5-year follow-up, with a total of 502 patient-years. At baseline, their median age was 47 years, median SLE disease duration was 14 years, 88% were women, 58% had lupus nephritis, and the median eGFR was 99 mL/min/1.73m

Indexed as

Coronary Artery DiseaseLupus Erythematosus, SystemicLupus NephritisVascular CalcificationAdultDisease ProgressionFemaleGlomerular Filtration RateHumansIncidenceLongitudinal StudiesMaleMiddle AgedMyocardial InfarctionRisk FactorsTomography, X-Ray ComputedAtherosclerosisCardiovascular risk factorsCoronary artery calcification progressionImpaired renal functionLupus nephritisMyocardial infarctionSLE

Identifiers

PMID39804493
PMCPMC11729070

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.