Evidence map›Paper›PMID 39804472›Full record

ArticleMikrochimica acta2025

Aptamer proximal enzyme cascade reactions for ultrafast detection of glucose in human blood serum.

Min Liu, Chuanlin Zhu, Zihe Dong, Zhangmin Wang, Huan Yang, Jie Li, Ke Li, Bo Shen, Xinmin Li, Ping Leng and 3 more

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Min Liu *College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Chuanlin Zhu *Department of Laboratory Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, China.
Zihe Dong *Department of Laboratory Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, China.
Zhangmin Wang *College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Huan YangCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Jie LiDepartment of Laboratory Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, China.
Ke LiDepartment of Clinical Medical Laboratory, Third People's Hospital of Chengdu, Southwest Jiaotong University Clinical Medical College/Soutwest Jiaotong University Affiliated Hospital, Chengdu, 610031, Sichuan, China.
Bo ShenDepartment of Laboratory Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, China.
Xinmin LiDepartment of Laboratory Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, China.
Ping LengCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Shijia DingKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Jinlin GuoCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Juan ZhangCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. zhangjuan@cdutcm.edu.cn.

Funding

Chongqing Natural Science Foundation Joint Fund for Innovation and Development CSTB2023NSCQ-LZX0007Chongqing scientific research institutions performance incentive and guidance project cstc2021jxjl130038National Natural Science Foundation of China 82202649
6 · The paper itself

Abstract

An innovative colorimetric sensing strategy was developed for the detection of glucose by the integration of glucose aptamer, glucose oxidase (GOx), and horseradish peroxidase (HRP), termed aptamer proximal enzyme cascade reactions (APECR). In the presence of glucose, aptamer binding enables GOx to catalyze glucose oxidation into H

Indexed as

Aptamers, NucleotideBiosensing TechniquesBlood GlucoseBenzothiazolesColorimetryGlucose OxidaseHorseradish PeroxidaseHumansHydrogen PeroxideLimit of DetectionOxidation-ReductionSulfonic Acids2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAptamers, NucleotideBenzothiazolesBlood GlucoseGlucose OxidaseHorseradish PeroxidaseHydrogen PeroxideSulfonic AcidsColorimetric sensing methodEnzyme cascade reactionsGlucose aptamerGlucose detectionGlucose oxidaseHorseradish peroxidase

Identifiers

PMID39804472

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.