ArticleInsights into imaging2025
Enhancing safety in CT-guided lung biopsies: correlation of MinIP imaging with pneumothorax risk prediction.
Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Reevaluating Routine Post-Biopsy Chest X-Rays After CT-Guided Lung Biopsy: Incidence of Pneumothorax and Value of Symptom-Based Monitoring.Journal of clinical medicine · 2025Article
- Impact of Technical Standardization on Pneumothorax and Chest Tube Insertion Rates: A Retrospective Learning Curve Analysis of CT-Guided Lung Biopsies.Journal of clinical medicine · 2025Article
- The role of gravitational effects and pre-puncture techniques in reducing pneumothorax during CT-guided lung biopsies.La Radiologia medica · 2025Article
- Ground-Glass Opacities in the Access Route and Biopsy in Highly Perfused Dependent Areas of the Lungs as Risk Factors for Pulmonary Hemorrhage During CT-Guided Lung Biopsy: A Retrospective Study.Tomography (Ann Arbor, Mich.) · 2025Article
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10 authors.
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Abstract
objectivesThis study aimed to evaluate whether minimum-intensity projection (MinIP) images could predict complications in CT-guided lung biopsies.
methodsWe retrospectively analyzed 72 procedures from January 2019 to December 2023, categorizing patients by pneumothorax and the severity of hemorrhage (grade 2 or higher). Radiodensity measurements were performed using lung window (LW) and MinIP (10-mm slab) images. Regions of interest (ROIs) were placed at sites of the lowest density along the biopsy pathway. Absolute values were recorded, categorized by a radiodensity level of -850 HU, and assessed using our bridged radiological observations with measurement-optimized model (BROM-OLB) model with validation from three additional ROIs. Emphysema was visually scored. Statistical analysis included univariate analysis (Fisher's exact and Mann-Whitney U-tests) and binomial logistic regression to identify confounders.
resultsLower radiodensity values in MinIP images in the access route, particularly with the BROM-OLB MinIP method, were significantly associated with a higher risk of pneumothorax (5/39, 13% vs 27/33, 82%, p < 0.01; Sensitivity 81.8% and Specificity 87.2%). Pneumothorax was more common with longer procedures (p < 0.05). Lower LW density values correlated with higher pulmonary hemorrhage rates (p < 0.01). Binomial logistic regression identified positive BROM-OLB MinIP results (OR 28.244, 95% CI: 7.675-103.9, p < 0.01) and lower LW density (OR 0.992, 95% CI: 0.985-0.999, p = 0.025) as independent risk factors. The optimal threshold values to predict pneumothorax were -868 HU in MinIP images and -769 HU in LW.
conclusionThe assessment of MinIP images is superior, and in combination with relative quantitative measurement of radiodensity for access route planning, it can reduce the risk of pneumothorax in CT-guided lung biopsies. CRITICAL RELEVANCE STATEMENT: This article critically evaluates the risk factors for complications in CT-guided lung biopsies, highlighting the potential of MinIP images for predicting pneumothorax risk, thereby advancing clinical radiology practices to improve patient safety and reduce healthcare costs. KEY POINTS: This work investigates if MinIP images efficiently predict CT-guided lung biopsy complications. MinIP imaging identified higher pneumothorax risk post-CT lung biopsy with superior accuracy. Our method detects high-risk lung changes linked to pneumothorax without additional software.
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