Evidence map›Paper›PMID 39804027›Full record

ArticleDisability and rehabilitation2025

A scoping review and synthesis of the literature on the relation between mobility impairment and cognitive impairment.

Payton D Rule, Victoria L Trammell, Patrick L Hill, Jennifer G Pearlstein, Emily C Willroth

Abstract readScoping Review
In one paragraph

Article in Disability and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Payton D RulePsychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Victoria L TrammellPsychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Patrick L HillPsychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Jennifer G PearlsteinAnesthesiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Emily C WillrothPsychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.

Funding

Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI Susan Lynn Stark · 2020 to 2026
$28.7M
Well-being as a Protective Factor against Cognitive Decline and Dementia RiskR00AG071838 · NIA · WASHINGTON UNIVERSITY · PI WILLROTH, EMILY C · 2022 to 2024
$853k
NIA NIH HHS P30 AG066444NIA NIH HHS R00 AG071838
6 · The paper itself

Abstract

PURPOSE/

objectiveThe present review examined the evidence for a potentially bidirectional association between mobility function and cognitive function in midlife and older adulthood. RESEARCH METHOD/

designIn 2023-2024, we conducted a scoping review by carrying out systematic searches on Google Scholar, PubMed, and PsycINFO for articles that included measures of mobility function and cognitive function.

resultsOf the 1,504 articles screened, 40 were included for review. The majority of reviewed studies found evidence of a relation between lower mobility function/greater mobility decline and lower cognitive function/greater cognitive decline. Prospective effects were observed in both directions; however, only five studies directly tested the bidirectionality of the association between mobility function and cognitive function. CONCLUSION/IMPLICATIONS: Individuals with lower mobility function may be more likely to experience declines in cognitive function and vice versa. More research is needed to further test the bidirectionality of this association and to identify protective factors that may disrupt this relation and reduce the incidence of co-occurring mobility impairment and cognitive impairment.

Indexed as

Cognitive DysfunctionMobility LimitationAgedHumansMiddle AgedcognitiondisabilityFunctioningimpairmentmobilityquality of life

Identifiers

PMID39804027
PMCPMC12255826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.