GuidelineDeutsches Arzteblatt international2025
Clinical Practice Guideline: The Diagnosis and Treatment of Osteoporosis.
Guideline in Deutsches Arzteblatt international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Artificial intelligence for opportunistic screening of osteoporosis across multiple imaging modalities: a systematic review.Frontiers in medicine · 2026Pooled it
- Association between immune-inflammatory index and osteoporosis: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- Effect of a one time guideline based educational video intervention on osteoporosis related knowledge.Archives of orthopaedic and trauma surgery · 2026Trial
- Age-related bone mineral density patterns in a large German clinical DXA cohort: device-specific comparisons with international reference populations.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Early Identification of Low Bone Density Risk Using a Radiofrequency Echographic Multi Spectrometry-Based Prediction Model.Life (Basel, Switzerland) · 2026Article
- Osteoporosis-related knowledge in a German adult population: determinants and translational implications for fragility fracture prevention.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Automated quantitative analysis of osteoclast numbers and areas in cell culture plates using the YOLOv8 instance segmentation model.MethodsX · 2026Article
- [Surgical stabilization of fragility fractures of the pelvis shows a good age-appropriate result regardless of the surgical procedure].Unfallchirurgie (Heidelberg, Germany) · 2026Article
- Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and osteoporotic fracture.Frontiers in medicine · 2026Article
- The recent progression of extracellular vesicles application in osteoporosis.Frontiers in pharmacology · 2026Review
- Dietary patterns and osteoporosis risk in a high-altitude population: the roles of gut microbiota and plasma metabolites in a case-control study.Frontiers in nutrition · 2026Article
- Vitamin D status in patients with arthritis and osteoporosis: a comparative analysis of inpatient and outpatient cohorts.Frontiers in endocrinology · 2026Article
- [Structured care of patients with osteoporosis in Germany : Disease Management Program and Fracture Liaison Service].Orthopadie (Heidelberg, Germany) · 2025Review
- Development and validation of a nomogram for osteoporosis based on clinical characteristics in Kunming.Journal of orthopaedic surgery and research · 2025Article
- Barriers and solutions for global access to osteoporosis management: a Position Paper from the International Osteoporosis Foundation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Review
- Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.Endocrine connections · 2025Article
- Characteristics and treatment options of 272,152 geriatric patients with very high and high fracture risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- In Reply.Deutsches Arzteblatt international · 2025Article
- Preventive Approach Should Be Strengthened.Deutsches Arzteblatt international · 2025Article
- Bariatric surgery and the risk for osteoporotic fractures - a population-based study.Archives of orthopaedic and trauma surgery · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis is a common disease that affects approximately 6 million people in Germany alone. Osteoporotic fractures impair the quality of life and may make independent living impossible. Recommendations on the diagnosis and treatment of osteoporosis are indispensable for the effective care of this large group of patients.
methodsFor a thorough updating of the German clinical practice guideline (an evidence-based guideline with recommendations for clinical practice) on osteoporosis, a comprehensive, systematic search for relevant publications was carried out, including guidelines from other countries. The retrieved literature was assessed with standardized (Oxford) criteria, and clinically relevant key questions were answered according to the PICO scheme ("population, intervention, comparison, outcomes").
resultsThe assessment of clinical risk factors for osteoporosis is the basis of osteoporosis diagnostics, which should be carried out quickly after a fracture. If risk factors are present in a postmenopausal woman or a man aged 50 or above, bone densitometry testing with dual-energy x-ray absorptiometry (DXA) is recommended. The further diagnostic evaluation should proceed in stepwise fashion depending on the clinical symptoms, the fracture status, and the degree of bone density reduction. Pharmacotherapy should be adapted to the fracture risk. Osteoanabolic treatment is recommended with high priority if the patient is judged to have a very high risk of fracture (10% or more in the next three years). The further course and duration of treatment should be determined individually, depending on the evolution of the patient's clinical state.
conclusionPrerequisites for the optimal treatment of patients with osteoporosis include a correct diagnosis and interdisciplinary and interprofessional collaboration to determine and provide the proper treatment. 71% of persons with osteoporosis in Germany are still untreated, and this gap must be closed.
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