Evidence map›Paper›PMID 39803923›Full record

ArticleTurkish archives of pediatrics2025

Microbial Contamination of Nebulizers in Patients With Cystic Fibrosis.

Cansu Yilmaz Yegit, Pinar Ergenekon, Nurcan Duman, Hakan Mursaloglu, Muruvvet Cenk, Burcu Suzer Uzunoglu, Gamze Tastan, Yasemin Gokdemir, Ela Erdem Eralp, Aysegul Karahasan Yagci and 2 more

Abstract read
In one paragraph

Article in Turkish archives of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cansu Yilmaz YegitDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.
Pinar ErgenekonDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.
Nurcan DumanDepartment of Microbiology, Marmara University School of Medicine, İstanbul, Türkiye.
Hakan MursalogluSelim Çöremen Cystic Fibrosis Center, Marmara University School of Medicine, İstanbul, Türkiye.
Muruvvet CenkDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.
Burcu Suzer UzunogluSelim Çöremen Cystic Fibrosis Center, Marmara University School of Medicine, İstanbul, Türkiye.
Gamze TastanSelim Çöremen Cystic Fibrosis Center, Marmara University School of Medicine, İstanbul, Türkiye.
Yasemin GokdemirDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.
Ela Erdem EralpDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.
Aysegul Karahasan YagciDepartment of Microbiology, Marmara University School of Medicine, İstanbul, Türkiye.
Fazilet KarakocDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.
Bulent KaradagDepartment of Pediatric Pulmonology, Marmara University School of Medicine, İstanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Nebulizer contamination has potential harmful effects on the respiratory system. The aim was to investigate the contamination profile of the nebulizers in cystic fibrosis patients and evaluate the relationship between hygiene practices and microbial contamination. Materials and Methods: Microbiological swab samples were taken from 3 different locations of the nebulizers of 102 patients. A questionnaire regarding nebulizer hygiene practices was applied to participants. Results: Contamination rate was 40.2%, while chambers were the most contaminated area. The bacterial contamination rate was 37.3%, with gram-negative bacterial growth being predominant. The organisms identified were mostly environmental or floral. Only 3 of the patients were performing the whole steps correctly. This number was not sufficient to assess the relationship between nebulizer cleaning and disinfection practices and microbial growth from nebulizers. When the relationship between nebulizer cleaning/disinfection frequencies, methods, and storage locations was evaluated separately with microbial growth from nebulizers, no statistically significant relationship was found for all (P > .05 for all). Conclusion: The nebulizer contamination rate with pathogenic microorganisms is low in the present study. Regular educational interventions regarding nebulizer hygiene practices should be implemented in all Cystic Fibrosis Centers.

Identifiers

PMID39803923
PMCPMC11736810

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.