Evidence map›Paper›PMID 39803895›Full record

ArticleSleep2025

Association between positive airway pressure therapy and healthcare costs among older adults with comorbid obstructive sleep apnea and common chronic conditions: an actuarial analysis.

Emerson M Wickwire, Chris R Fernandez, Nhan Huynh, Nathaniel F Watson, Ian Duncan

Abstract read
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In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Untreated obstructive sleep apnea and accelerated cognitive decline over 10 years.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Emerson M WickwireDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Chris R FernandezEnsoData, Madison, WI, USA.
Nhan HuynhSanta Barbara Actuaries Inc., Santa Barbara, CA, USA.
Nathaniel F WatsonEnsoData, Madison, WI, USA.
Ian DuncanSanta Barbara Actuaries Inc., Santa Barbara, CA, USA.

Funding

EnsoData
6 · The paper itself

Abstract

STUDY

objectivesTo determine the association between adherence to positive airway pressure and healthcare costs among a national sample of older adults with comorbid obstructive sleep apnea (OSA) and common chronic conditions.

methodsOur data source was a random sample of Medicare administrative claims for years 2016-2019. Inclusion criteria included age ≥65 years and new diagnosis of OSA. Exclusion criteria included evidence of prior OSA treatment during the 12 months prior to the index date, active cancer, or end-stage renal disease. OSA was defined using physician-assigned diagnostic codes. Common chronic conditions included chronic obstructive pulmonary disease, congestive heart failure, depression, hypertension, type 2 diabetes mellitus, obesity, and stroke. Based on Medicare policy, individuals were classified as adherers, nonadherers, or noninitiators. Risk adjustment was based on the Centers for Medicare and Medicaid Hierarchical Condition Categories approach developed by the Centers for Medicaid and Medicare Service specifically to estimate anticipated costs. To examine the impact of PAP adherence on costs, we employed a weighted DID regression framework to account for baseline variations in health status and other confounding factors.

resultsParticipants included 28 220 Medicare beneficiaries with comorbid OSA. Of these, 45% were adherent to PAP, 10% were nonadherent, and 44% did not initiate PAP. Relative to noninitiators, beneficiaries who initiated PAP displayed $195 reduced per-member per-month costs over 24 months. This finding remained consistent across all seven medical and psychiatric subgroups, as well as among individuals with multimorbidity.

conclusionsIn this national analysis of Medicare beneficiaries with common chronic conditions, PAP adherence was associated with reduced costs over 24 months.

Indexed as

Continuous Positive Airway PressureHealth Care CostsSleep Apnea, ObstructiveAgedAged, 80 and overChronic DiseaseComorbidityFemaleHumansMaleMedicarePatient ComplianceUnited Statesadherencecostshealth economicsMedicareobstructive sleep apneaolder adultspositive airway pressure

Identifiers

PMID39803895

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.